Solid-State Conformational Flexibility at Work: Zipping and Unzipping within a Cyclic Peptoid Single Crystal

被引：38

作者：

Meli, Alessandra ^{[1
]}

Macedi, Eleonora ^{[1
]}

De Riccardis, Francesco ^{[1
]}

Smith, Vincent J. ^{[2
]}

Barbour, Leonard J. ^{[2
]}

Izzo, Irene ^{[1
]}

Tedesco, Consiglia ^{[1
]}

机构：

[1] Univ Salerno, Dipartimento Chim & Biol A Zambelli, Via Giovanni Paolo II 132, I-84084 Fisciano, SA, Italy

[2] Univ Stellenbosch, Dept Chem & Polymer Sci, Private Bag X1, ZA-7602 Stellenbosch, South Africa

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2016年 / 55卷 / 15期

关键词：

crystal engineering; host-guest systems; noncovalent interactions; peptoids; supramolecular chemistry; HYDROGEN-BONDS; GUEST;

D O I：

10.1002/anie.201511053

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A peptidomimetic compound undergoes a reversible single-crystal-to-single-crystal transformation upon guest release/uptake with the transformation involving a drastic conformational change. The extensive and reversible alteration in the solid state is connected to the formation of an unprecedented CH- zipper which can reversibly open and close (through the formation of CH- interactions), thus allowing for guest sensing.

引用

页码：4679 / 4682

页数：4

共 49 条

[1] [Anonymous], 2013, ANGEW CHEM
[2] [Anonymous], 2004, ANGEW CHEM
[3] A new type of material for the recovery of hydrogen from gas mixtures
Atwood, JL
Barbour, LJ
Jerga, A
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (22) : 2948 - 2950
[4] Guest transport in a nonporous organic solid via dynamic van der Waals cooperativity
Atwood, JL
Barbour, LJ
Jerga, A
Schottel, BL
[J]. SCIENCE, 2002, 298 (5595) : 1000 - 1002
[5] A SYSTEM FOR STUDYING GAS SOLID REACTION-KINETICS IN CONTROLLED ATMOSPHERES
BARBOUR, LJ
ACHLEITNER, K
GREENE, JR
[J]. THERMOCHIMICA ACTA, 1992, 205 : 171 - 177
[6] Berg J.M., 2008, BIOCH LOOSE LEAF
[7] Advances in kinetic protein crystallography
Bourgeois, D
Royant, A
[J]. CURRENT OPINION IN STRUCTURAL BIOLOGY, 2005, 15 (05) : 538 - 547
[8] Braga D., 2007, MAKING CRYSTALS DESI
[9] Making molecular machines work
Browne, Wesley R.
Feringa, Ben L.
[J]. NATURE NANOTECHNOLOGY, 2006, 1 (01) : 25 - 35
[10] Bureekaew S., 2010, ANGEW CHEM, V122, P7826

← 1 2 3 4 5 →