共 9 条
[1]
Untangling asthma phenotypes and endotypes
[J].
Agache, I.
;
Akdis, C.
;
Jutel, M.
;
Virchow, J. C.
.
ALLERGY,
2012, 67 (07)
:835-846

Agache, I.
论文数: 0 引用数: 0
h-index: 0
机构:
Transylvania Univ Brasov, Dept Allergy & Clin Immunol, Fac Med, Brasov, Romania Transylvania Univ Brasov, Dept Allergy & Clin Immunol, Fac Med, Brasov, Romania

Akdis, C.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland Transylvania Univ Brasov, Dept Allergy & Clin Immunol, Fac Med, Brasov, Romania

Jutel, M.
论文数: 0 引用数: 0
h-index: 0
机构:
Wroclaw Med Univ, Dept Clin Immunol, PL-50368 Wroclaw, Poland Transylvania Univ Brasov, Dept Allergy & Clin Immunol, Fac Med, Brasov, Romania

Virchow, J. C.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Clin Rostock, Dept Pulmonol, Zentrum Innere Med, Klin 1, Rostock, Germany Transylvania Univ Brasov, Dept Allergy & Clin Immunol, Fac Med, Brasov, Romania
[2]
Epithelial cell dysfunction, a major driver of asthma development
[J].
Heijink, Irene H.
;
Kuchibhotla, Virinchi N. S.
;
Roffel, Mirjam P.
;
Maes, Tania
;
Knight, Darryl A.
;
Sayers, Ian
;
Nawijn, Martijn C.
.
ALLERGY,
2020, 75 (08)
:1902-1917

Heijink, Irene H.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands
Univ Groningen, Univ Med Ctr Groningen, Dept Pulmonol, Groningen, Netherlands Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands

Kuchibhotla, Virinchi N. S.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands
Univ Newcastle, Sch Biomed Sci & Pharm, Callaghan, NSW, Australia Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands

Roffel, Mirjam P.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands
Univ Ghent, Ghent Univ Hosp, Dept Resp Med, Lab Translat Res Obstruct Pulm Dis, Ghent, Belgium Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands

Maes, Tania
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Ghent, Ghent Univ Hosp, Dept Resp Med, Lab Translat Res Obstruct Pulm Dis, Ghent, Belgium Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands

Knight, Darryl A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Newcastle, Sch Biomed Sci & Pharm, Callaghan, NSW, Australia
UBC Providence Hlth Care Res Inst, Vancouver, BC, Canada
Univ British Columbia, Dept Anesthesiol Pharmacol & Therapeut, Vancouver, BC, Canada Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands

Sayers, Ian
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Nottingham, Univ Nottingham Biodiscovery Inst, Natl Inst Hlth Res, Div Resp Med,Nottingham Biomed Res Ctr, Nottingham, England Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands

Nawijn, Martijn C.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Dept Pathol & Med Biol, Groningen, Netherlands
[3]
DNA methylation in lung cells is associated with asthma endotypes and genetic risk
[J].
Nicodemus-Johnson, Jessie
;
Myers, Rachel A.
;
Sakabe, Noburu J.
;
Sobreira, Debora R.
;
Hogarth, Douglas K.
;
Naureckas, Edward T.
;
Sperling, Anne I.
;
Solway, Julian
;
White, Steven R.
;
Nobrega, Marcelo A.
;
Nicolae, Dan L.
;
Gilad, Yoav
;
Ober, Carole
.
JCI INSIGHT,
2016, 1 (20)

Nicodemus-Johnson, Jessie
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Myers, Rachel A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Sakabe, Noburu J.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Sobreira, Debora R.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Hogarth, Douglas K.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Naureckas, Edward T.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Sperling, Anne I.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Solway, Julian
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

White, Steven R.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Nobrega, Marcelo A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Nicolae, Dan L.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA
Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA
Univ Chicago, Dept Stat, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Gilad, Yoav
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA
Univ Chicago, Dept Med, 5841 S Maryland Ave, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA

Ober, Carole
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA Univ Chicago, Dept Human Genet, 920 E 58th St, Chicago, IL 60637 USA
[4]
DNA demethylation regulates gene expression in IgE-activated mouse mast cells
[J].
Paivandy, Aida
;
Grujic, Mirjana
;
Rafati, Nima
;
Pejler, Gunnar
.
ALLERGY,
2020, 75 (07)
:1776-1780

Paivandy, Aida
论文数: 0 引用数: 0
h-index: 0
机构:
Uppsala Univ, Dept Med Biochem & Microbiol, Uppsala, Sweden Uppsala Univ, Dept Med Biochem & Microbiol, Uppsala, Sweden

Grujic, Mirjana
论文数: 0 引用数: 0
h-index: 0
机构:
Uppsala Univ, Dept Med Biochem & Microbiol, Uppsala, Sweden Uppsala Univ, Dept Med Biochem & Microbiol, Uppsala, Sweden

Rafati, Nima
论文数: 0 引用数: 0
h-index: 0
机构:
Uppsala Univ, Dept Med Biochem & Microbiol, Sci Life Lab, Uppsala, Sweden
Uppsala Univ, Sci Life Lab, NBIS, Uppsala, Sweden Uppsala Univ, Dept Med Biochem & Microbiol, Uppsala, Sweden

Pejler, Gunnar
论文数: 0 引用数: 0
h-index: 0
机构:
Uppsala Univ, Dept Med Biochem & Microbiol, Uppsala, Sweden
Swedish Univ Agr Sci, Dept Anat Physiol & Biochem, Uppsala, Sweden Uppsala Univ, Dept Med Biochem & Microbiol, Uppsala, Sweden
[5]
Outside-in hypothesis revisited The role of microbial, epithelial, and immune interactions
[J].
Sugita, Kazunari
;
Soyka, Michael B.
;
Wawrzyniak, Paulina
;
Rinaldi, Arturo O.
;
Mitamura, Yasutaka
;
Akdis, Mubeccel
;
Akdis, Cezmi A.
.
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY,
2020, 125 (05)
:517-527

Sugita, Kazunari
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland
Christine Kuhne Ctr Allergy Res & Educ, Davos, Switzerland
Tottori Univ, Fac Med, Dept Med Sensory & Motor Organs, Div Dermatol, Yonago, Tottori 6838504, Japan Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland

Soyka, Michael B.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland
Univ Zurich, Dept Otorhinolaryngol Head & Neck Surg, Zurich, Switzerland
Univ Hosp Zurich, Zurich, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland

Wawrzyniak, Paulina
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Childrens Hosp Zurich, Div Clin Chem & Biochem, Zurich, Switzerland
Univ Childrens Hosp Zurich, Childrens Res Ctr, Zurich, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland

Rinaldi, Arturo O.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland

Mitamura, Yasutaka
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland
Christine Kuhne Ctr Allergy Res & Educ, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland

论文数: 引用数:
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Akdis, Cezmi A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland
Christine Kuhne Ctr Allergy Res & Educ, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, Davos, Switzerland
[6]
Epigenetic drug discovery: breaking through the immune barrier
[J].
Tough, David F.
;
Tak, Paul P.
;
Tarakhovsky, Alexander
;
Prinjha, Rab K.
.
NATURE REVIEWS DRUG DISCOVERY,
2016, 15 (12)
:835-853

Tough, David F.
论文数: 0 引用数: 0
h-index: 0
机构:
GlaxoSmithKline, Epinova Epigenet Discovery Performance Unit, Immunoinflammat Therapy Area, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline, Epinova Epigenet Discovery Performance Unit, Immunoinflammat Therapy Area, Med Res Ctr, Stevenage SG1 2NY, Herts, England

Tak, Paul P.
论文数: 0 引用数: 0
h-index: 0
机构:
GlaxoSmithKline Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline, Epinova Epigenet Discovery Performance Unit, Immunoinflammat Therapy Area, Med Res Ctr, Stevenage SG1 2NY, Herts, England

Tarakhovsky, Alexander
论文数: 0 引用数: 0
h-index: 0
机构:
Rockefeller Univ, Lab Immune Cell Epigenet & Signaling, New York, NY 10065 USA GlaxoSmithKline, Epinova Epigenet Discovery Performance Unit, Immunoinflammat Therapy Area, Med Res Ctr, Stevenage SG1 2NY, Herts, England

Prinjha, Rab K.
论文数: 0 引用数: 0
h-index: 0
机构:
GlaxoSmithKline, Epinova Epigenet Discovery Performance Unit, Immunoinflammat Therapy Area, Med Res Ctr, Stevenage SG1 2NY, Herts, England GlaxoSmithKline, Epinova Epigenet Discovery Performance Unit, Immunoinflammat Therapy Area, Med Res Ctr, Stevenage SG1 2NY, Herts, England
[7]
Regulation of bronchial epithelial barrier integrity by type 2 cytokines and histone deacetylases in asthmatic patients
[J].
Wawrzyniak, Paulina
;
Wawrzyniak, Marcin
;
Wanke, Kerstin
;
Sokolowska, Milena
;
Bendelja, Kreso
;
Ruckert, Beate
;
Globinska, Anna
;
Jakiela, Bogdan
;
Kast, Jeannette I.
;
Idzko, Marco
;
Akdis, Mubeccel
;
Sanak, Marek
;
Akdis, Cezmi A.
.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY,
2017, 139 (01)
:93-103

Wawrzyniak, Paulina
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Wawrzyniak, Marcin
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Wanke, Kerstin
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Sokolowska, Milena
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Bendelja, Kreso
论文数: 0 引用数: 0
h-index: 0
机构:
Inst Immunol, Zagreb, Croatia Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Ruckert, Beate
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Globinska, Anna
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Jakiela, Bogdan
论文数: 0 引用数: 0
h-index: 0
机构:
Jagiellonian Univ, Coll Med, Dept Med, PL-31007 Krakow, Poland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Kast, Jeannette I.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Idzko, Marco
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Freiburg, Dept Pneumol, Freiburg, Germany Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

论文数: 引用数:
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Sanak, Marek
论文数: 0 引用数: 0
h-index: 0
机构:
Jagiellonian Univ, Coll Med, Dept Med, PL-31007 Krakow, Poland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland

Akdis, Cezmi A.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland Univ Zurich, Swiss Inst Allergy & Asthma Res SIAF, CK CARE, Davos, Switzerland
[8]
Molecular Modeling Studies of the Novel Inhibitors of DNA Methyltransferases SGI-1027 and CBC12: Implications for the Mechanism of Inhibition of DNMTs
[J].
Yoo, Jakyung
;
Choi, Sun
;
Medina-Franco, Jose L.
.
PLOS ONE,
2013, 8 (04)

Yoo, Jakyung
论文数: 0 引用数: 0
h-index: 0
机构:
Ewha Womans Univ, Div Life & Pharmaceut Sci, Coll Pharm, Natl Leading Res Lab Mol Modeling & Drug Design, Seoul, South Korea
Ewha Womans Univ, Global Res Program Top5, Seoul, South Korea Ewha Womans Univ, Div Life & Pharmaceut Sci, Coll Pharm, Natl Leading Res Lab Mol Modeling & Drug Design, Seoul, South Korea

论文数: 引用数:
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Medina-Franco, Jose L.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico Ewha Womans Univ, Div Life & Pharmaceut Sci, Coll Pharm, Natl Leading Res Lab Mol Modeling & Drug Design, Seoul, South Korea
[9]
DNA methylation and allergic sensitizations: A genome-scale longitudinal study during adolescence
[J].
Zhang, Hongmei
;
Kaushal, Akhilesh
;
Merid, Simon Kebede
;
Melen, Erik
;
Pershagen, Goran
;
Rezwan, Faisal I.
;
Han, Luhang
;
Ewart, Susan
;
Arshad, S. Hasan
;
Karmaus, Wilfried
;
Holloway, John W.
.
ALLERGY,
2019, 74 (06)
:1166-1175

Zhang, Hongmei
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Kaushal, Akhilesh
论文数: 0 引用数: 0
h-index: 0
机构:
Baylor Coll Med, Ctr Precis Environm Hlth, Houston, TX 77030 USA Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Merid, Simon Kebede
论文数: 0 引用数: 0
h-index: 0
机构:
Karolinska Inst, Inst Environm Med, Stockholm, Sweden Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Melen, Erik
论文数: 0 引用数: 0
h-index: 0
机构:
Karolinska Inst, Inst Environm Med, Stockholm, Sweden
Sachs Childrens Hosp, Stockholm, Sweden Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Pershagen, Goran
论文数: 0 引用数: 0
h-index: 0
机构:
Karolinska Inst, Inst Environm Med, Stockholm, Sweden Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Rezwan, Faisal I.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Southampton, Fac Med Clin & Expt Sci, Southampton, Hants, England Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Han, Luhang
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Memphis, Dept Math Sci, Memphis, TN 38152 USA Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Ewart, Susan
论文数: 0 引用数: 0
h-index: 0
机构:
Michigan State Univ, Coll Vet Med, E Lansing, MI 48824 USA Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

Arshad, S. Hasan
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Southampton, Fac Med Clin & Expt Sci, Southampton, Hants, England
David Hide Asthma & Allergy Res Ctr, Newport, Wight, England Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA

论文数: 引用数:
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Holloway, John W.
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Southampton, Fac Med Clin & Expt Sci, Southampton, Hants, England
Univ Southampton, Human Dev & Hlth, Fac Med, Southampton, Hants, England Univ Memphis, Sch Publ Hlth, Div Epidemiol Biostat & Environm Hlth Sci, Memphis, TN 38152 USA