A compass for stem-cell differentiation

被引：4

作者：

Mueller, Franz-Josef ^{[1
]}

Loring, Jeanne F. ^{[2
]}

机构：

[1] Univ Klinikum Schleswig Holstein, Zentrum Integrat Psychiat Kiel, D-24105 Kiel, Germany

[2] Scripps Res Inst, Dept Physiol Chem, Ctr Regenerat Med, La Jolla, CA 92037 USA

来源：

NATURE | 2014年 / 513卷 / 7519期

关键词：

DEFINED FACTORS; DIRECT CONVERSION; FIBROBLASTS;

D O I：

10.1038/513498a

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The development of CellNet — network-biology software that determines how cell types generated in vitro relate to their naturally occurring counterparts — could improve our ability to produce desirable cells in culture.

引用

页码：498 / 499

页数：2

共 9 条

[1]

[Anonymous], 2014, The strategy of the genes

[2] CellNet: Network Biology Applied to Stem Cell Engineering [J].

Cahan, Patrick ;

Li, Hu ;

Morris, Samantha A. ;

da Rocha, Edroaldo Lummertz ;

Daley, George Q. ;

Collins, James J. .

CELL, 2014, 158 (04) :903-915

[3] Dissecting Engineered Cell Types and Enhancing Cell Fate Conversion via CellNet [J].

Morris, Samantha A. ;

Cahan, Patrick ;

Li, Hu ;

Zhao, Anna M. ;

Roman, Adrianna K. San ;

Shivdasani, Ramesh A. ;

Collins, James J. ;

Daley, George Q. .

CELL, 2014, 158 (04) :889-902

[4] Regulatory networks define phenotypic classes of human stem cell lines [J].

Mueller, Franz-Josef ;

Laurent, Louise C. ;

Kostka, Dennis ;

Ulitsky, Igor ;

Williams, Roy ;

Lu, Christina ;

Park, In-Hyun ;

Rao, Mahendra S. ;

Shamir, Ron ;

Schwartz, Philip H. ;

Schmidt, Nils O. ;

Loring, Jeanne F. .

NATURE, 2008, 455 (7211) :401-U55

[5] A bioinformatic assay for pluripotency in human cells [J].

Mueller, Franz-Josef ;

Schuldt, Bernhard M. ;

Williams, Roy ;

Mason, Dylan ;

Altun, Gulsah ;

Papapetrou, Eirini P. ;

Danner, Sandra ;

Goldmann, Johanna E. ;

Herbst, Arne ;

Schmidt, Nils O. ;

Aldenhoff, Josef B. ;

Laurent, Louise C. ;

Loring, Jeanne F. .

NATURE METHODS, 2011, 8 (04) :315-U54

[6] Direct conversion of mouse fibroblasts to hepatocyte-like cells by defined factors [J].

Sekiya, Sayaka ;

Suzuki, Atsushi .

NATURE, 2011, 475 (7356) :390-U148

[7] Timeline - Conrad Hal Waddington: the last renaissance biologist? [J].

Slack, JMW .

NATURE REVIEWS GENETICS, 2002, 3 (11) :889-895

[8] Induction of pluripotent stem cells from adult human fibroblasts by defined factors [J].

Takahashi, Kazutoshi ;

Tanabe, Koji ;

Ohnuki, Mari ;

Narita, Megumi ;

Ichisaka, Tomoko ;

Tomoda, Kiichiro ;

Yamanaka, Shinya .

CELL, 2007, 131 (05) :861-872

[9] Direct conversion of fibroblasts to functional neurons by defined factors [J].

Vierbuchen, Thomas ;

Ostermeier, Austin ;

Pang, Zhiping P. ;

Kokubu, Yuko ;

Suedhof, Thomas C. ;

Wernig, Marius .

NATURE, 2010, 463 (7284) :1035-U50

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