A System Review of Anti-fibrogenesis Effects of Compounds Derived from Chinese Herbal Medicine

被引：9
作者：
Zhao, Yanling [1 ]
Ma, Xiao [1 ,2 ]
Wang, Jiabo [1 ]
He, Xuan [3 ]
Zhang, Yaming [1 ]
Wang, Ye [4 ]
Liu, Honghong [5 ]
Shen, Honghui [1 ]
Xiao, Xiaohe [1 ]
机构：
[1] 302 Mil Hosp China, China Mil Inst Chinese Med, Beijing 100039, Peoples R China
[2] Chengdu Univ Tradit Chinese Med, Coll Pharm, Chengdu 611137, Peoples R China
[3] Sichuan Univ, West China Hosp, State Key Lab Biotherapy, Chengdu 610041, Peoples R China
[4] 302 Mil Hosp China, Dept Outpatient, Beijing 100039, Peoples R China
[5] 302 Mil Hosp China, Dept Integrat Med Ctr, Beijing 100039, Peoples R China
来源：
MINI-REVIEWS IN MEDICINAL CHEMISTRY | 2016年 / 16卷 / 02期
关键词：
Chinese herbal medicine; Extracellular matrix; Hepatic stellate cell; Liver fibrosis; HEPATIC STELLATE CELLS; INDUCED LIVER FIBROSIS; SWEET-POTATO ATTENUATE; SALVIANOLIC ACID B; CARBON-TETRACHLORIDE; SIGNALING PATHWAY; RAT-LIVER; IN-VITRO; PPAR-GAMMA; COLLAGEN PRODUCTION;
D O I：
10.2174/1389557515666150709121908
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Chinese herbal medicine (CHM), an alternative and complementary medicine, has been applied in various diseases. Recently, a number of anti-liver fibrogenesis compounds exhibiting anti-liver fibrosis effects have been discovered in CHM. In this review, we reviewed the published data on their anti-fibrosis effects and discussed the possible underlying mechanisms. More investigations are needed to improve the insight into therapeutic effect of CHM on liver fibrosis.
引用
收藏
页码：163 / 175
页数：13
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