Adherence of extracellular matrix components to modified surfaces of titanium alloys

被引：8

作者：

Stelzer, C. ^{[2
]}

Uhlmann, E. ^{[2
]}

Meinke, M. ^{[1
]}

Lademann, J. ^{[1
]}

Hansen, U. ^{[3
]}

机构：

[1] Charite Univ Med Berlin, Dept Dermatol & Allergol, Ctr Expt Appl Cutaneous Physiol, D-10117 Berlin, Germany

[2] Tech Univ Berlin, Inst Machine Tools & Factory Management, D-10587 Berlin, Germany

[3] Univ Hosp Muenster, Dept Physiol Chem & Pathobiochem, D-48149 Munster, Germany

来源：

LASER PHYSICS LETTERS | 2009年 / 6卷 / 04期

关键词：

laser machining; laser-based technology; TiAl6V4; surfaces; coating; extracellular matrix components; LASER-SCANNING MICROSCOPY; PENETRATION; FIBRILS;

D O I：

10.1002/lapl.200810131

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

The adherence of biological materials on metal surfaces is of special importance in biology and medicine. The underlying interactions between surface and biological materials (e.g. extracellular matrix components or cells) are responsible for the application as a medical device. Numerous products are made of pure titanium and titanium alloys. This paper shows the influence of a laser production technology on machined surfaces of TiAl6V4 and the resulting adherence of biological material on the basis of the surface characterisation. In this study, different machined TiAl6V4 surfaces were used for coatings with extracellular matrix components. For this process, different coating with collagen I monomers and a complex mixture of extracellular matrix proteins derived from the dermal-epidermal basement membrane zone were analysed. The efficiency of the coating was analysed by different methods and the results are presented in this paper.

引用

页码：311 / 316

页数：6

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