Formulation, Characterization, and In Vitro Mineral Absorption of Ficus Palmata Fruit Extract Nanoemulsion

被引:10
|
作者
Prashar, Sagar [1 ]
Sharma, Somesh [1 ]
Kumar, Naveen [2 ]
Kaushik, Ravinder [3 ]
Chawla, Prince [4 ]
机构
[1] Shoolini Univ, Solan, Himachal Prades, India
[2] Amity Univ Rajasthan, Jaipur, Rajasthan, India
[3] Univ Petr & Energy Studies, Dehra Dun, Uttarakhand, India
[4] Lovely Profess Univ, Phagwara, Punjab, India
来源
JOURNAL OF THE AMERICAN NUTRITION ASSOCIATION | 2022年 / 41卷 / 03期
关键词
Nanoemulsion; Ficus palmata; Bioavailability; Minerals; Zeta potential; Gum arabic;
D O I
10.1080/07315724.2021.1879693
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Objective Loss of vital bioactive components of Ficus palmata fruit extract during food processing is a major issue. Therefore, to retain the antioxidant potential and to increase the mineral bioavailability, gum arabic stabilized nanoemulsion of Fig fruit extract was prepared. Method . Nanoemulsion was formulated using three different levels (1, 3, and 5%) of fig extract, however, to optimize the fig extract concentration, the amount of gum arabic and linoleic acid was kept constant. Results The average droplet size of nanoemulsion was observed in the range of 22.88-37.87 nm, whereas the Fourier Transform Infrared (FTIR) Spectroscopy confirmed the presence of functional groups in the emulsion system. Also, increased ionic concentration significantly (p < 0.05) increased the average droplet size and zeta potential of nanoemulsion during storage. Increased shear rate and temperature unveiled a slight decrease in apparent viscosity of the nanoemulsion. Non-significant (p < 0.05) difference in TBA value confirmed the oxidative stability of the emulsion. Significantly (p < 0.05) higher mineral bioavailability for calcium was observed as compared to iron and zinc. Conclusion Our results manifested improved anti-oxidant activity, mineral bioavailability, and oxidative stability of Fig extract nanoemulsion, suggesting its potential use as a therapeutic alternative.
引用
收藏
页码:291 / 300
页数:10
相关论文
共 39 条
  • [11] Formulation and characterization of nanoemulsion containing anthocyanin extract from purple yam (Dioscorea alata L.)
    Tamaroh, Siti
    Sari, Yuli Perwita
    Wariyah, Chatarina
    Huda, Nurul
    Candraruna, Dipta Bthari
    FOOD SCIENCE AND BIOTECHNOLOGY, 2025, 34 (04) : 905 - 911
  • [12] Development and in vitro characterization nanoemulsion containing the methanol extract of Hypericum linarioides for wound healing: In vitro scratch assay
    Kaplan, Afife Busra Ugur
    Yesilyurt, Fatma
    Guven, Leyla
    Cetin, Meltem
    Lacin, Burak Batuhan
    Ozkaraca, Mustafa
    Yilmaz, Mustafa Abdullah
    Hacimuftuoglu, Ahmet
    Kaya, Yusuf
    SOUTH AFRICAN JOURNAL OF BOTANY, 2024, 168 : 316 - 327
  • [13] Characterization, stability, digestion and absorption of a nobiletin nanoemulsion using DHA-enriched phosphatidylcholine as an emulsifier in vivo and in vitro
    Ju, Sheng-Nan
    Shi, Hao-Hao
    Yang, Jin-Yue
    Zhao, Ying-Cai
    Xue, Chang-Hu
    Wang, Yu-Ming
    Huang, Qing-Rong
    Zhang, Tian-Tian
    FOOD CHEMISTRY, 2022, 397
  • [14] Formulation and characterization of chlorhexidine HCl nanoemulsion as a promising antibacterial root canal irrigant: in-vitro and ex-vivo studies
    Abdelmonem, Rehab
    Younis, Mona K.
    Hassan, Doaa H.
    Ahmed, Mohamed Abd El-Gawad El-Sayed
    Hassanein, Ehab
    El-Batouty, Kariem
    Elfaham, Alaa
    INTERNATIONAL JOURNAL OF NANOMEDICINE, 2019, 14 : 4697 - 4708
  • [15] In vitro/in vivo characterization of nanoemulsion formulation of metronidazole with improved skin targeting and anti-rosacea properties
    Yu, Meng
    Ma, Huixian
    Lei, Mingzhu
    Li, Nan
    Tan, Fengping
    EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2014, 88 (01) : 92 - 103
  • [16] Formulation and in vitro characterization of nanoemulsions containing remdesivir or licorice extract: A potential subcutaneous injection for coronavirus treatment
    Al Ashmawy, Al Zahraa G.
    Balata, Gehan F.
    COLLOIDS AND SURFACES B-BIOINTERFACES, 2024, 234
  • [17] Formulation Development, Optimization by Box-Behnken Design, and In Vitro Characterization of Gefitinib Phospholipid Complex Based Nanoemulsion Drug Delivery System
    Mohit
    Kumar, Pankaj
    Solanki, Pavitra
    Mangla, Bharti
    Aggarwal, Geeta
    JOURNAL OF PHARMACEUTICAL INNOVATION, 2023, 18 (03) : 952 - 964
  • [18] Omega 3 fatty acid-enriched nanoemulsion of thiocolchicoside for transdermal delivery: formulation, characterization and absorption studies
    Kumar, Dinesh
    Ali, Javed
    Baboota, Sanjula
    DRUG DELIVERY, 2016, 23 (02) : 591 - 600
  • [19] Optimization and Characterization of Palm Oil-based Nanoemulsion Loaded with Parthenium hysterophorus Crude Extract for Natural Herbicide Formulation
    Zainuddin, Noorul Jannah
    Ashari, Siti Efliza
    Salim, Norazlinaliza
    Asib, Norhayu
    Omar, Dzolkhifli
    Lian, Gwendoline Ee Cheng
    JOURNAL OF OLEO SCIENCE, 2019, 68 (08) : 747 - 757
  • [20] Physiochemical Characterization of Nanoemulsion Formulation of Phenazine and their Antifungal Efficacy against Ganoderma Boninense PER71 in vitro
    Lee, Kai Wei
    bin Omar, Dzolkhifli
    bt Abdan, Khalina
    Wong, Mui Yun
    RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES, 2016, 7 (06): : 3056 - 3066