Successful treatment of kerion with itraconazole and ALA-PDT: A case report

被引：10

作者：

Lu, Jiejie ^{[1
]}

Li, Wen ^{[1
]}

Zheng, Wen'ai ^{[2
]}

Huang, Ruiye ^{[1
]}

Wu, Weiwei ^{[1
]}

机构：

[1] Fifth Peoples Hosp Hainan Prov, Dept Dermatol, 33 Southern Rd Longkun, Haikou 570206, Hainan, Peoples R China

[2] Fifth Peoples Hosp Hainan Prov, Dept Lab Med, 33 Southern Rd Longkun, Haikou 570206, Hainan, Peoples R China

来源：

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY | 2019年 / 27卷

基金：

海南省自然科学基金;

关键词：

Kerion; Photodynamic therapy; Aminolevulinic acid; ltraconazole;

D O I：

10.1016/j.pdpdt.2019.07.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Kerion refers to the severe inflammatory reaction which occurs in some cases of fungal infection of the hair or hair follicles. Successful treatment is a challenge for the small number of kerion patients who show poor efficacy of oral antifungal agents. In recent years, photodynamic therapy (PDT) has been proven to be a useful treatment for a variety of fungal infections. In this case report, a 9-year-old Chinese girl presented with erythema, pustular and tender plaques on her scalp for 2 month. The diagnosis of kerion was made based on clinical features and positive mycological findings. After the disease relapsed with oral administration of itraconazole for 6 weeks, she was successfully cured by three sessions of ALA-PDT combined with itraconazole. This case report suggests that ALA-PDT provides a good alternative and adjutant choice for kerion with safety, less side effects, and good repeatability.

引用

页码：385 / 387

页数：3

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