Strategies to improve stimulation efficiency for retinal prostheses

被引:0
作者
Davuluri, Navya S. [1 ,2 ]
Nimmagadda, Kiran [3 ,4 ]
Petrossians, Artin [5 ,6 ]
Humayun, Mark S. [1 ,6 ]
Weiland, James D. [1 ,6 ]
机构
[1] Univ Southern Calif, Dept Biomed Engn, Los Angeles, CA 90089 USA
[2] Samsung Strategy & Innovat Ctr, San Jose, CA 95134 USA
[3] Univ Southern Calif, Neurosci Grad Program, Los Angeles, CA 90089 USA
[4] Univ Southern Calif, MD PhD Program, Los Angeles, CA 90089 USA
[5] Univ Southern Calif, Mork Family Dept Chem Engn & Mat Sci, Los Angeles, CA 90089 USA
[6] Univ Southern Calif, Dept Ophthalmol, Los Angeles, CA 90089 USA
来源
2016 38TH ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC) | 2016年
关键词
ELECTRICAL-STIMULATION; RETINITIS-PIGMENTOSA; RAT; TRANSPLANTATION; RESPONSES; LIGHT; MODEL;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Retinitis Pigmentosa (RP) is a degenerative disease of the retina that leads to vision loss. Retinal prostheses are being developed in order to restore functional vision in patients suffering from RP. We conducted in-vivo experiments in order to identify strategies to efficiently stimulate the retina. We electrically stimulated the retina and measured electrically evoked potentials (EERs) from the superior colliculus of rats. We compared the strength of EERs when voltage-controlled and current-controlled pulses of varying pulse width and charge levels were applied to the retina. In addition to comparing EER strength, we evaluated improvement in power efficiency afforded by a high surface area platinum-iridium material. Voltage-controlled pulses were more efficient than current-controlled pulses when the pulses have a short duration (< 1 ms) and current-controlled pulses were more efficient than voltage-controlled pulses when the pulse width was greater than 1 ms. The high surface area platinum-iridium stimulation electrode consumed power significantly lower than a standard platinum-iridium electrode.
引用
收藏
页码:3133 / 3138
页数:6
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