Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial

被引:13
作者
Motaharifard, Monireh Sadat [1 ]
Effatpanah, Mohammad [2 ]
Karimi, Mehrdad [1 ]
Akhondzadeh, Shahin [3 ]
Rahimi, Habibollah [4 ]
Yasrebi, Seyed Ali [5 ]
Nejatbakhsh, Fatemeh [1 ]
机构
[1] Univ Tehran Med Sci, Sch Tradit Med, Dept Iranian Tradit Med, Tehran, Iran
[2] Univ Tehran Med Sci, Ziaeian Hosp, Sch Med, Int Campus, Tehran, Iran
[3] Univ Tehran Med Sci, Roozbeh Hosp, Psychiat Res Ctr, Tehran, Iran
[4] Kashan Univ Med Sci, Clin Res Dev Unit Matini, Kargarnejad Hosp, Kashan, Iran
[5] Ferdowsi Univ Mashhad, Fac Sci, Dept Chem, Mashhad, Razavi Khorasan, Iran
关键词
sweet almond; DHD; Persian Medicine; Iranian Traditional Medicine; functional food; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT-HYPERACTIVITY DISORDER; PRUNUS-AMYGDALUS; GINKGO-BILOBA; COMPLEMENTARY; PREVALENCE;
D O I
10.1016/j.ctcp.2019.07.008
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Background and purpose: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common health disorders among children. Some patients do not respond to methylphenidate or cannot tolerate its side effects. Sweet almond syrup as a Persian Medicine preparation has been used for many years. This study aims to evaluate the efficacy and safety of sweet almond for ADHD children. Materials and methods: Fifty children aged 6-14 years with ADHD were recruited to the study. The participants were randomly assigned to two groups to receive either methylphenidate or sweet almond syrup. The outcomes were assessed using the Parent and Teacher ADHD Rating Scale every two weeks for 8 weeks. Results: Results showed that the two treatments had similar effects on symptom reduction in ADHD children. No significant differences were observed between the two groups (F = 2.3, df = 1, p = 0.13, F = 0.57, df = 1, p = 0.47). Conclusion: Sweet almond may be an effective treatment for ADHD children.
引用
收藏
页码:170 / 175
页数:6
相关论文
共 40 条
[21]   DIETARY BORON, BRAIN-FUNCTION, AND COGNITIVE PERFORMANCE [J].
PENLAND, JG .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1994, 102 :65-72
[22]  
Pizzorno Lara, 2015, Integr Med (Encinitas), V14, P35
[23]   The worldwide prevalence of ADHD: A systematic review and metaregression analysis [J].
Polanczyk, Guilherme ;
de Lima, Mauricio Silva ;
Horta, Bernardo Lessa ;
Biederman, Joseph ;
Rohde, Luis Augusto .
AMERICAN JOURNAL OF PSYCHIATRY, 2007, 164 (06) :942-948
[24]   ADHD prevalence estimates across three decades: an updated systematic review and meta-regression analysis [J].
Polanczyk, Guilherme V. ;
GWillcutt, Erik ;
Salum, Giovanni A. ;
Kieling, Christian ;
Rohde, Luis A. .
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY, 2014, 43 (02) :434-442
[25]   Immunostimulant activity of dry fruits and plant materials used in Indian traditional medical system for mothers after child birth and invalids [J].
Puri, A ;
Sahai, R ;
Singh, KL ;
Saxena, RP ;
Tandon, JS ;
Saxena, KC .
JOURNAL OF ETHNOPHARMACOLOGY, 2000, 71 (1-2) :89-92
[26]   Phytochemical investigations and evaluation of antidiabetic potential of Prunus dulcis nuts [J].
Qureshi, Muhammad Nasimullah ;
Numonov, Sodik ;
Abudurexiti, Ajigu ;
Aisa, Haji Akber .
LWT-FOOD SCIENCE AND TECHNOLOGY, 2016, 66 :311-317
[27]   Omega-3 fatty acids in ADHD and related neurodevelopmental disorders [J].
Richardson, Alexandra J. .
INTERNATIONAL REVIEW OF PSYCHIATRY, 2006, 18 (02) :155-172
[28]   An update on the diagnosis and treatment of attention-deficit/hyperactivity disorder in children [J].
Root, RW ;
Resnick, RJ .
PROFESSIONAL PSYCHOLOGY-RESEARCH AND PRACTICE, 2003, 34 (01) :34-41
[29]  
SAHIB ZH, 2014, MED J BABYLON, V11, P817
[30]   Ginkgo biloba for Attention-Deficit/Hyperactivity Disorder in children and adolescents: A double blind, randomized controlled trial [J].
Salehi, Bahman ;
Imani, Reza ;
Mohammadi, Mohammad Reza ;
Fallah, Jalil ;
Mohammadi, Mohammad ;
Ghanizadeh, Ahmad ;
Tasviechi, Ali Akbar ;
Vossoughi, Ardalan ;
Rezazadeh, Shams-Ali ;
Akhondzadeh, Shahin .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 2010, 34 (01) :76-80