Effect of sweet almond syrup versus methylphenidate in children with ADHD: A randomized triple-blind clinical trial

被引：13

作者：

Motaharifard, Monireh Sadat ^{[1
]}

Effatpanah, Mohammad ^{[2
]}

Karimi, Mehrdad ^{[1
]}

Akhondzadeh, Shahin ^{[3
]}

Rahimi, Habibollah ^{[4
]}

Yasrebi, Seyed Ali ^{[5
]}

Nejatbakhsh, Fatemeh ^{[1
]}

机构：

[1] Univ Tehran Med Sci, Sch Tradit Med, Dept Iranian Tradit Med, Tehran, Iran

[2] Univ Tehran Med Sci, Ziaeian Hosp, Sch Med, Int Campus, Tehran, Iran

[3] Univ Tehran Med Sci, Roozbeh Hosp, Psychiat Res Ctr, Tehran, Iran

[4] Kashan Univ Med Sci, Clin Res Dev Unit Matini, Kargarnejad Hosp, Kashan, Iran

[5] Ferdowsi Univ Mashhad, Fac Sci, Dept Chem, Mashhad, Razavi Khorasan, Iran

来源：

COMPLEMENTARY THERAPIES IN CLINICAL PRACTICE | 2019年 / 36卷

关键词：

sweet almond; DHD; Persian Medicine; Iranian Traditional Medicine; functional food; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT-HYPERACTIVITY DISORDER; PRUNUS-AMYGDALUS; GINKGO-BILOBA; COMPLEMENTARY; PREVALENCE;

D O I：

10.1016/j.ctcp.2019.07.008

中图分类号：

R [医药、卫生];

学科分类号：

10 ;

摘要：

Background and purpose: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common health disorders among children. Some patients do not respond to methylphenidate or cannot tolerate its side effects. Sweet almond syrup as a Persian Medicine preparation has been used for many years. This study aims to evaluate the efficacy and safety of sweet almond for ADHD children. Materials and methods: Fifty children aged 6-14 years with ADHD were recruited to the study. The participants were randomly assigned to two groups to receive either methylphenidate or sweet almond syrup. The outcomes were assessed using the Parent and Teacher ADHD Rating Scale every two weeks for 8 weeks. Results: Results showed that the two treatments had similar effects on symptom reduction in ADHD children. No significant differences were observed between the two groups (F = 2.3, df = 1, p = 0.13, F = 0.57, df = 1, p = 0.47). Conclusion: Sweet almond may be an effective treatment for ADHD children.

引用

页码：170 / 175

页数：6

共 40 条

[1]

Akhondzadeh S., 2005, Therapy, V2, P609, DOI DOI 10.2217/14750708.2.4.609

[2] Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children: A double blind and randomized trial [ISRCTN64132371] [J].

Akhondzadeh, Shahin ;

Mohammadi, Mohammad-Reza ;

Khademi, Mojgan .

BMC PSYCHIATRY, 2004, 4 (1)

[3]

Barker J., 2004, ALT COMP THERAP, V10, P131

[4] Repeated administration of almonds increases brain acetylcholine levels and enhances memory function in healthy rats while attenuates memory deficits in animal model of amnesia [J].

Batool, Zehra ;

Sadir, Sadia ;

Liaquat, Laraib ;

Tabassum, Saiqa ;

Madiha, Syeda ;

Rafiq, Sahar ;

Tariq, Sumayya ;

Batool, Tuba Sharf ;

Saleem, Sadia ;

Naqvi, Fizza ;

Perveen, Tahira ;

Haider, Saida .

BRAIN RESEARCH BULLETIN, 2016, 120 :63-74

[5] Almond ingestion at mealtime reduces postprandial glycemia and chronic ingestion reduces hemoglobin A1c in individuals with well-controlled type 2 diabetes mellitus [J].

Cohen, Ashley E. ;

Johnston, Carol S. .

METABOLISM-CLINICAL AND EXPERIMENTAL, 2011, 60 (09) :1312-1317

[6]

Dave Usha Pinakin, 2014, Adv Mind Body Med, V28, P10

[7] Flavanols and Anthocyanins in Cardiovascular Health: A Review of Current Evidence [J].

de Pascual-Teresa, Sonia ;

Moreno, Diego A. ;

Garcia-Viguera, Cristina .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2010, 11 (04) :1679-1703

[8] Attention-Deficit-Hyperactivity Disorder: An Update [J].

Dopheide, Julie A. ;

Pliszka, Steven R. .

PHARMACOTHERAPY, 2009, 29 (06) :656-679

[9]

DSM-5, 2013, DIAGNOSTIC STAT MANU, DOI DOI 10.1176/APPI.BOOKS.9780890425596

[10] The importance of almond (Prunus amygdalus L.) and its by-products [J].

Esfahlan, Ali Jahanban ;

Jamei, Rashid ;

Esfahlan, Rana Jahanban .

FOOD CHEMISTRY, 2010, 120 (02) :349-360

← 1 2 3 4 →