Acute percutaneous lactic acid poisoning in a child

被引:22
作者
Esteban Ramirez, Manuela
Fasheh Youseef, Wael
Garrido Romero, Roser
Quintilla Martinez, Jose Maria
Gonzalez-Ensenat, Maria Antonia
Sanmarti Vilaplana, Xavier
Luaces Cubells, Carles
机构
[1] Univ Barcelona, Hosp St Joan Deu, Dept Pediat, Serv Pediat,Deu Hosp Clin, Barcelona 08950, Spain
[2] Univ Barcelona, Hosp St Joan Deu, Serv Dermatol, Deu Hosp Clin, Barcelona 08950, Spain
[3] Univ Barcelona, Hosp St Joan Deu, Neurol Serv, Deu Hosp Clin,Integrated Pediat Unit,Emergency Se, Barcelona 08950, Spain
关键词
D O I
10.1111/j.1525-1470.2006.00236.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Percutaneous poisoning is quite rare, and in particular, topical lactic acid poisoning is even more so. We report a young girl with lamellar ichthyosis and symptoms of poisoning, with clinical signs of irritability, agitation, myoclonia, and difficulty in walking, accompanied by lactic acidosis as a result of the more frequent than recommended application of emollients containing lactic acid. The clinical symptoms resolved upon discontinuation of the topical treatment. Among the possible causes of metabolic acidosis, health care providers should be aware of the possibility of percutaneous poisoning.
引用
收藏
页码:282 / 285
页数:4
相关论文
共 22 条
[1]   Pediatric toxicologic deaths - A 10-year retrospective study [J].
Campbell, TA ;
Collins, KA .
AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY, 2001, 22 (02) :184-187
[2]   Transglutaminase 1 mutations in lamellar ichthyosis - Loss of activity due to failure of activation by proteolytic processing [J].
Candi, E ;
Melino, G ;
Lahm, A ;
Ceci, R ;
Rossi, A ;
Kim, IG ;
Ciani, B ;
Steinert, PM .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (22) :13693-13702
[3]   Salicylate intoxication using a skin ointment [J].
Chiaretti, A ;
Wismayer, DS ;
Tortorolo, L ;
Piastra, M ;
Polidori, G .
ACTA PAEDIATRICA, 1997, 86 (03) :330-331
[4]  
DELTORO M, 2001, DIAGNOSTICO TRAITAMI, P149
[5]   Poisoning in children: Indian scenario. [J].
Dutta A.K. ;
Seth A. ;
Goyal P.K. ;
Aggarwal V. ;
Mittal S.K. ;
Sharma R. ;
Bahl L. ;
Thakur J.S. ;
Verma M. ;
Chhatwal J. ;
Chacko B. ;
Saini V. ;
Singhal A. ;
Sharma P. ;
Sharma U. ;
Chaturvedi P. ;
Kumar S. ;
Prajapati N.C. ;
Vaidya J. ;
Garg N. ;
Basu S.N. ;
Lahiri M. ;
Das C.K. ;
Pal D.K. ;
Lall S.B. .
The Indian Journal of Pediatrics, 1998, 65 (3) :365-370
[6]   Basis for the permeability barrier abnormality in lamellar ichthyosis [J].
Elias, PM ;
Schmuth, M ;
Uchida, Y ;
Rice, RH ;
Behne, M ;
Crumrine, D ;
Feingold, KR ;
Holleran, WM ;
Pharm, D .
EXPERIMENTAL DERMATOLOGY, 2002, 11 (03) :248-256
[7]   HYPEROSMOLALITY INDUCED BY PROPYLENE-GLYCOL - A COMPLICATION OF SILVER SULFADIAZINE THERAPY [J].
FLIGNER, CL ;
JACK, R ;
TWIGGS, GA ;
RAISYS, VA .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1985, 253 (11) :1606-1609
[8]   Improved topical treatment of lamellar ichthyosis:: a double-blind study of four different cream formulations [J].
Gånemo, A ;
Virtanen, M ;
Vahlquist, A .
BRITISH JOURNAL OF DERMATOLOGY, 1999, 141 (06) :1027-1032
[9]  
GRIFFITHS WAD, 1992, TXB DERMATOLOGY, P1339
[10]   Acute household propylene glycol intoxication in a two-year-old toddler: about an unusual case report [J].
Guillot, M ;
Bocquet, G ;
Eckart, P ;
Amiour, M ;
El-Hachem, C ;
Garnier, R ;
Galliot-Guilley, M ;
Haguenoer, JM .
ARCHIVES DE PEDIATRIE, 2002, 9 (04) :382-384