Optimising Care of Elderly Breast Cancer Patients: a Challenging Priority

被引：6

作者：

Tipples, K. ^{[1
]}

Robinson, A. ^{[1
]}

机构：

[1] Southend Univ Hosp NHS Fdn Trust, Dept Oncol, Westcliff On Sea SS0 0RY, Essex, England

来源：

CLINICAL ONCOLOGY | 2009年 / 21卷 / 02期

关键词：

Breast cancer; chemotherapy; elderly; endocrine therapy; COMPREHENSIVE GERIATRIC ASSESSMENT; POSTMENOPAUSAL WOMEN; ADJUVANT THERAPY; OLDER PATIENTS; AROMATASE INHIBITORS; RANDOMIZED-TRIAL; DOUBLE-BLIND; INTERNATIONAL-SOCIETY; ENDOCRINE THERAPY; CHEMOTHERAPY;

D O I：

10.1016/j.clon.2008.11.015

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Elderly breast cancer patients comprise almost 50% of the breast cancer population. The unique needs of this population are discussed. Therapeutic challenges facing clinicians include the absence of the ideal method to assess these patients' fitness to receive therapy, to anticipate probable side-effects and to predict survival. In addition, there are few guidelines to assist decision-making, as historically clinical trials have excluded such individuals. Evidence for the use of chemotherapy, endocrine therapy and newer targeted therapies in the elderly is summarised. Special safety considerations in the elderly are highlighted and current practice and ongoing research are reviewed. Tipples, K., Robinson, A. (2009). Clinical Oncology 21, 118-130 (C) 2008 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

引用

页码：118 / 130

页数：13

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