Opportunities in posthemorrhagic hydrocephalus research: outcomes of the Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop

被引：42

作者：

Koschnitzky, Jenna E. ^{[1
]}

Keep, Richard F. ^{[2
]}

Limbrick, David D., Jr. ^{[3
]}

McAllister, James P., II ^{[3
]}

Morris, Jill A. ^{[4
]}

Strahle, Jennifer ^{[3
]}

Yung, Yun C. ^{[5
]}

机构：

[1] Hydrocephalus Assoc, 4340 East West Highway, Bethesda, MD 20814 USA

[2] Univ Michigan, 1500 East Med Ctr Dr, Ann Arbor, MI 48109 USA

[3] Washington Univ, Sch Med, 660 S Euclid Ave, St Louis, MO 63110 USA

[4] Natl Inst Neurol Disorders & Stroke, NIH, Neurosci Ctr, 6001 Execut Blvd,NSC Rm 2112, Bethesda, MD 20892 USA

[5] Sanford Burnham Prebys Med Discovery Inst, 10901 North Torrey Pines Rd, La Jolla, CA 92037 USA

来源：

FLUIDS AND BARRIERS OF THE CNS | 2018年 / 15卷

关键词：

Hydrocephalus; Posthemorrhagic; Intraventricular hemorrhage; Germinal matrix hemorrhage; Blood brain barrier; Premature; LOW-BIRTH-WEIGHT; SEVERE INTRAVENTRICULAR HEMORRHAGE; ENDOSCOPIC 3RD VENTRICULOSTOMY; CHOROID-PLEXUS CAUTERIZATION; NEURAL STEM-CELLS; MINOCYCLINE-INDUCED ATTENUATION; CEREBROSPINAL-FLUID BIOMARKERS; GERMINAL MATRIX HEMORRHAGE; BLOOD-PRESSURE REDUCTION; NEONATAL PIGLET MODEL;

D O I：

10.1186/s12987-018-0096-3

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The Hydrocephalus Association Posthemorrhagic Hydrocephalus Workshop was held on July 25 and 26, 2016 at the National Institutes of Health. The workshop brought together a diverse group of researchers including pediatric neurosurgeons, neurologists, and neuropsychologists with scientists in the fields of brain injury and development, cerebrospinal and interstitial fluid dynamics, and the blood-brain and blood-CSF barriers. The goals of the workshop were to identify areas of opportunity in posthemorrhagic hydrocephalus research and encourage scientific collaboration across a diverse set of fields. This report details the major themes discussed during the workshop and research opportunities identified for posthemorrhagic hydrocephalus. The primary areas include (1) preventing intraventricular hemorrhage, (2) stopping primary and secondary brain damage, (3) preventing hydrocephalus, (4) repairing brain damage, and (5) improving neurodevelopment outcomes in posthemorrhagic hydrocephalus.

引用

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