Semiquantitative study of current coffee, caffeine, and ethanol intake in essential tremor cases and controls

被引:25
作者
Louis, ED
Jurewicz, EC
Applegate, L
Luchsinger , JA
Factor-Litvak, P
Parides, M
机构
[1] Columbia Univ Coll Phys & Surg, Inst Neurol, Gertrude H Sergievsky Ctr, New York, NY 10032 USA
[2] Columbia Univ Coll Phys & Surg, Dept Neurol, New York, NY 10032 USA
[3] Columbia Univ, Coll Phys & Surg, Taub Inst Alzheimers Dis & Aging Brain, New York, NY USA
[4] Columbia Univ Coll Phys & Surg, Dept Med, New York, NY 10032 USA
[5] Columbia Univ, Mailman Sch Publ Hlth, Dept Epidemiol, New York, NY USA
[6] Columbia Univ, Mailman Sch Publ Hlth, Dept Biostat, New York, NY USA
关键词
essential tremor; coffee; caffeine; alcohol; epidemiology;
D O I
10.1002/mds.20035
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
There are several reasons to Study caffeine, coffee, and ethanol intake in essential tremor (ET) patients. ET patients also might modify their use of these beverages because of their effects on tremor. Intake of caffeine. coffee, and ethanol has not been quantified in a group of ET patients. Our objective is to use a semiquantitative food frequency questionnaire to compare Current daily intake of coffee. caffeine, and ethanol in ET patients and controls. A total of 130 ET cases were patients at the Neurological Institute of New York, and 175 controls were ascertained by random digit dialing. Caffeine (in milligrams) and ethanol (in grams) intake were calculated from a semiquantitative food-frequency questionnaire. Mean daily caffeine intake in patients was 138.4 versus 246.6 mg in controls; medians were 101.1 versus 175.5 mg (P < 0.001). Mean daily ethanol intake in patients was 8.2 versus 6.2 gm in controls; medians were 2.4 versus 1.9 gm (P = 0.89). Cases drank less coffee than controls, but drank similar amounts of tea, soft drinks, fruit juices, and milk. Daily caffeine intake was not correlated with tremor severity or duration. ET patients Consumed less caffeine than did controls, which is likely to be a dietary modification in response to tremor. The observation that caffeine consumption was not correlated with tremor severity raises the additional possibility that lower caffeine consumption in ET patients may not exclusively be a response to tremor. A prospective Study is needed to explore whether decreased caffeine consumption is a risk factor for ET. (C) 2004 Movement Disorder Society.
引用
收藏
页码:499 / 504
页数:6
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