Antioxidant Properties of Probiotic Bacteria

被引：697

作者：

Wang, Yang ^{[1
]}

Wu, Yanping ^{[1
]}

Wang, Yuanyuan ^{[1
]}

Xu, Han ^{[1
]}

Mei, Xiaoqiang ^{[1
]}

Yu, Dongyou ^{[1
]}

Wang, Yibing ^{[1
]}

Li, Weifen ^{[1
]}

机构：

[1] Zhejiang Univ, Key Lab Mol Anim Nutr, Minist Educ, Inst Feed Sci,Coll Anim Sci, Hangzhou 310058, Zhejiang, Peoples R China

来源：

NUTRIENTS | 2017年 / 9卷 / 05期

基金：

中国国家自然科学基金;

关键词：

oxidative stress; antioxidant; probiotic; signaling pathway; gut microbiota; ACTIVATED PROTEIN-KINASE; HEAT-SHOCK PROTEINS; FATTY LIVER-DISEASE; RED-SEA BREAM; NF-KAPPA-B; OXIDATIVE STRESS; GUT MICROBIOTA; LACTOBACILLUS-PLANTARUM; SUPEROXIDE-DISMUTASE; TRANSCRIPTION FACTOR;

D O I：

10.3390/nu9050521

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Oxidative stress defines a condition in which the prooxidant-antioxidant balance in the cell is disturbed, resulting in DNA hydroxylation, protein denaturation, lipid peroxidation, and apoptosis, ultimately compromising cells' viability. Probiotics have been known for many beneficial health effects, and the consumption of probiotics alone or in food shows that strain-specific probiotics can present antioxidant activity and reduce damages caused by oxidation. However, the oxidation-resistant ability of probiotics, especially the underling mechanisms, is not properly understood. In this view, there is interest to figure out the antioxidant property of probiotics and summarize the mode of action of probiotic bacteria in antioxidation. Therefore, in the present paper, the antioxidant mechanisms of probiotics have been reviewed in terms of their ability to improve the antioxidant system and their ability to decrease radical generation. Since in recent years, oxidative stress has been associated with an altered gut microbiota, the effects of probiotics on intestinal flora composition are also elaborated.

引用

页数：15

共 133 条

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