Cardiac electrical and structural alterations in preeclampsia

被引:10
作者
Aksu, Ekrem [1 ]
Cuglan, Bilal [2 ]
Tok, Abdullah [1 ]
Celik, Enes [1 ]
Doganer, Adem [3 ,4 ]
Sokmen, Abdullah [1 ]
Sokmen, Gulizar [1 ]
机构
[1] Sutcu Imam Univ, Fac Med, Dept Cardiol, Kahramanmaras, Turkey
[2] Beykent Univ, Dept Cardiol, Fac Med, Cumhuriyet Mah Safak Sokak 1, Istanbul, Turkey
[3] Sutcu Imam Univ, Fac Med, Dept Biostat, Kahramanmaras, Turkey
[4] Sutcu Imam Univ, Fac Med, Dept Biostat, Kahramanmaras, Turkey
关键词
Arrhythmia; electromechanical delay; fQRS; myocardial performance index; preeclampsia; P-WAVE DISPERSION; TP-E/QT RATIO; ATRIAL-FIBRILLATION; FRAGMENTED QRS; VENTRICULAR REPOLARIZATION; E INTERVAL; ECG; ECLAMPSIA; INDEXES; MARKERS;
D O I
10.1080/14767058.2021.1895742
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background Preeclampsia increases the risk of cardiovascular mortality and morbidity both during pregnancy and long term after the labor by causing cardiac changes that may lead to atrial and ventricular arrhythmias. Objective We aimed to investigate noninvasive predictors of atrial and ventricular arrhythmias and cardiac structural changes in preeclampsia. Methods The study included 34 preeclampsia patients as the study group and 33 healthy pregnant women as the control group. The presence of fragmented QRS morphology, P dispersion, QT dispersion, Tp-e/QTc ratio, inter- and intra-atrial electromechanical delay, left ventricular mass index was evaluated in the groups by 12 lead- ECG and standard and tissue Doppler echocardiography. Results Left ventricular mass index and relative wall thickness, and E/Em ratio was significantly higher in preeclampsia. Inter- and intra-atrial electromechanical delay and Tp-e were prolonged, and P dispersion, QT dispersion, and Tp-e/QTc ratio were increased significantly in patients with preeclampsia. In addition, fragmented QRS morphology was seen in 76.5% of patients with preeclampsia while it was present in only 27.3% of the control group (p < .001). Conclusion Preeclampsia causes significant cardiac structural and electrocardiographic alterations that may increase the risk of atrial and/or ventricular arrhythmias. A more thorough and earlier cardiac assessment and closer follow-up of these patients would be useful to avoid further complications.
引用
收藏
页码:1 / 10
页数:10
相关论文
共 34 条
[11]   Comparison of atrial electromechanical coupling interval and P-wave dispersion in non-dipper versus dipper hypertensive subjects [J].
Ermis, Necip ;
Acikgoz, Nusret ;
Cuglan, Bilal ;
Cansel, Mehmet ;
Yagmur, Julide ;
Tasolar, Hakan ;
Barutcu, Irfan ;
Pekdemir, Hasan ;
Ozdemir, Ramazan .
BLOOD PRESSURE, 2011, 20 (01) :60-66
[12]   PATTERNS OF LEFT-VENTRICULAR HYPERTROPHY AND GEOMETRIC REMODELING IN ESSENTIAL-HYPERTENSION [J].
GANAU, A ;
DEVEREUX, RB ;
ROMAN, MJ ;
DESIMONE, G ;
PICKERING, TG ;
SABA, PS ;
VARGIU, P ;
SIMONGINI, I ;
LARAGH, JH .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1992, 19 (07) :1550-1558
[13]   Tp-e/QT ratio as an index of arrhythmogenesis [J].
Gupta, Prasad ;
Patel, Chinmay ;
Patel, Harsh ;
Narayanaswamy, Srinivasa ;
Malhotra, Binu ;
Green, Jared T. ;
Yan, Gan-Xin .
JOURNAL OF ELECTROCARDIOLOGY, 2008, 41 (06) :567-574
[14]   P-Wave Dispersion and Atrial Electromechanical Delay in Patients with Preeclampsia [J].
Inci, Sinan ;
Nar, Gokay ;
Aksan, Gokhan ;
Sipahioglu, Haydar ;
Soylu, Korhan ;
Dogan, Ali .
MEDICAL PRINCIPLES AND PRACTICE, 2015, 24 (06) :515-521
[15]   Fragmented ECG as a Risk Marker in Cardiovascular Diseases [J].
Jain, Rahul ;
Singh, Robin ;
Yamini, Sundermurthy ;
Das, Mithilesh K. .
CURRENT CARDIOLOGY REVIEWS, 2014, 10 (03) :277-286
[16]   New Markers for Ventricular Repolarization in Coronary Slow Flow: Tp-e Interval, Tp-e/QT Ratio, and Tp-e/QTc Ratio [J].
Karaman, Kayihan ;
Altunkas, Fatih ;
Cetin, Mustafa ;
Karayakali, Metin ;
Arisoy, Arif ;
Akar, Ilker ;
Zencir, Cemil ;
Ayguc, Baris ;
Celik, Atac .
ANNALS OF NONINVASIVE ELECTROCARDIOLOGY, 2015, 20 (04) :338-344
[17]   Novel indexes of arrhythmogenesis in preeclampsia: QT dispersion, Tp-e interval, and Tp-e/QT ratio [J].
Kirbas, Ayse ;
Kirbas, Ozgur ;
Daglar, Korkut ;
Inal, Hasan Ali ;
Kurmus, Ozge ;
Kara, Ozgur ;
Timur, Hakan ;
Gencosmanoglu, Gulenay ;
Danisman, Nuri .
PREGNANCY HYPERTENSION-AN INTERNATIONAL JOURNAL OF WOMENS CARDIOVASCULAR HEALTH, 2016, 6 (01) :38-41
[18]   P-wave duration changes and dispersion in preeclampsia [J].
Kirbas, Ozgur ;
Biberoglu, Ebru Hacer ;
Kirbas, Ayse ;
Daglar, Halil Korkut ;
Kurmus, Ozge ;
Uygur, Dilek ;
Danisman, Nuri .
EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 2014, 183 :141-145
[19]  
Letsas KP, 2010, EUROPACE, V12, P271, DOI 10.1093/europace/eup357
[20]   P Wave Indices Current Status and Future Directions in Epidemiology, Clinical, and Research Applications [J].
Magnani, Jared W. ;
Williamson, Mary Ann ;
Ellinor, Patrick T. ;
Monahan, Kevin M. ;
Benjamin, Emelia J. .
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY, 2009, 2 (01) :72-79