Effects of Environmental Endocrine-Disrupting Chemicals on Female Reproductive Health

被引:4
作者
Liu, Qicai [1 ]
机构
[1] Fujian Med Univ, Affiliated Hosp 1, Ctr Reprod Med, Fuzhou, Peoples R China
来源
ENVIRONMENT AND FEMALE REPRODUCTIVE HEALTH | 2021年 / 1300卷
关键词
EDCs; Reproductive disorders; CGRP; Hormone; Receptors; PCOS; BISPHENOL-A CONCENTRATIONS; THYROID-HORMONE HOMEOSTASIS; MAMMARY-GLAND DEVELOPMENT; POLYCYSTIC-OVARY-SYNDROME; GENE-EXPRESSION; IN-UTERO; AROMATASE-ACTIVITY; FAMILY PEPTIDES; SMALL EXPOSURES; DOWN-REGULATION;
D O I
10.1007/978-981-33-4187-6_10
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Environmental endocrine-disrupting chemicals (EDCs) are xenobiotic compounds that are frequently contacted in daily life. With the species and quantity of substances created and utilized by human beings significantly surpassing the self-purification capacity of nature, a large number of hazardous substances are enriched in the human body through the respiratory tract, digestive tract, and skin. Some of these compounds cause many problems endangering female reproductive health by simulating/antagonizing endogenous hormones or affecting the synthesis, metabolism, and bioavailability of endogenous hormones, including reproductive disorders, fetal birth defects, fetal developmental abnormalities, endocrine and metabolic disorders, and even gynecological malignancies. Therefore, the study of the relationship between environmental EDCs and female reproductive diseases and related mechanisms is of considerable significance to women, children health care, and improve the quality of the population.
引用
收藏
页码:205 / 229
页数:25
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