Optimization of MR diffusion-weighted imaging acquisitions for pancreatic cancer at 3.0 T

被引:4
作者
Yao, Xiuzhong [1 ,2 ]
Kuang, Tiantao [3 ]
Wu, Li [1 ,2 ]
Feng, Hao [1 ,2 ]
Liu, Hao [1 ,2 ]
Cheng, Weizhong [1 ,2 ]
Rao, Shengxiang [1 ,2 ]
Wang, He [4 ]
Zeng, Mengsu [1 ,2 ]
机构
[1] Fudan Univ, Zhongshan Hosp, Dept Radiol, Shanghai 200032, Peoples R China
[2] Fudan Univ, Shanghai Med Coll, Shanghai Inst Med Imaging, Dept Med Image, Shanghai 200032, Peoples R China
[3] Fudan Univ, Zhongshan Hosp, Dept Gen Surg, Shanghai 200032, Peoples R China
[4] GE Healthcare, Global Appl Sci Lab, Shanghai 201203, Peoples R China
关键词
Magnetic resonance imaging; 3.0; T; Diffusion-weighted imaging; Pancreatic cancer; COEFFICIENT; LIVER; QUALITY; LESIONS;
D O I
10.1016/j.mri.2014.04.011
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Objectives: To investigate and optimize diffusion-weighted imaging (DWI) acquisitions for pancreatic cancer at 3.0 T. Methods: Forty-five patients with pancreatic cancer were examined by four DWI acquisitions with b values = 0 and 600 s/mm(2) at 3.0 T, including breath-holding DWI (BH-DWI), respiratory-triggered DWI (TRIG-DWI), respiratory-triggered DWI with inversion-recovery technique (TRIGIR-DWI), and free-breathing DWI with inversion-recovery technique (FBIR-DWI). Artifacts, contrast ratio (CR), contrast-to-noise ratio (CNR) and apparent diffusion coefficient (ADC) of pancreatic cancer were statistically compared among DWI acquisitions. Results: TRIGIR-DWI displayed the lowest artifacts and highest CR compared to other DWI acquisitions. CNRs of pancreatic cancer in TRIG-DWI and TRIGIR-DWI were statistically higher than that in FBIR-DWI and BH-DWI. Different ADCs between pancreatic cancer and noncancerous pancreatic tissues were noticed by a paired-samples T test in TRIG-DWI (p = 0.017), TRIGIR-DWI (p = 0.00001) and FBIR-DWI (p = 0.000041). Conclusions: TRIGIR-DWI may be the optimal acquisition of DWI for pancreatic cancer at 3.0 T. (C) 2014 Elsevier Inc. All rights reserved.
引用
收藏
页码:875 / 879
页数:5
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