Nutritional status, adiposity and asthma severity and control in children

被引:3
作者
Silveira, Denise Halpern [1 ,3 ]
Zhang, Linjie [3 ]
Prietsch, Silvio O. M. [3 ]
Vecchi, Amilcare Angelo [2 ]
Odeh Susin, Lulie Rosane [3 ]
机构
[1] Univ Fed Pelotas, Sch Nutr, Pelotas, Brazil
[2] Univ Fed Pelotas, Fac Med, Pelotas, Brazil
[3] Fed Univ Rio Grande, Postgrad Program Hlth, Fac Med, Rio Grande, RS, Brazil
关键词
adiposity; asthma; body mass index; case control study; child; obesity; CHILDHOOD OBESITY; PERSISTENT ASTHMA; ASSOCIATION; PERSPECTIVE; MANAGEMENT; GUIDELINE; HEALTH; RISK;
D O I
10.1111/jpc.12882
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
AimTo investigate association between nutritional status, adiposity and asthma severity and control in children. MethodsWe conducted a case control study at two teaching hospitals in Brazil. Cases were children (3-12 years) with persistent asthma and age-matched controls were those with intermittent asthma. Nutritional status was assessed by body mass index (BMI). Adiposity was assessed by sum of skinfolds and waist circumference (WC). Crude and adjusted odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated using conditional logistic regression or multinomial logistic regression as appropriate. ResultsTwo hundred sixty-eight cases and 126 controls were included. Obesity (>2 BMIz-score for age) was significantly associated with persistent asthma (adjusted OR 2.62; 95% CI 1.39-4.95). There was a significant linear relationship between BMIz-scores (1, >1 to 2, >2) and risk of having persistent asthma (P = 0.003 for linear trend). Children with WC >90th percentile had a higher risk of persistent asthma when compared with those with WC 90th percentile (adjusted OR 3.38; 95% CI 1.26-9.06). No significant difference was found in terms of nutritional status and adiposity between children whose asthma was controlled by inhaled corticosteroids and those requiring inhaled corticosteroids plus other medications for asthma control. ConclusionsObesity measured by BMI and increased abdominal adiposity are significantly associated with risk of persistent asthma but not type of controller medications.
引用
收藏
页码:1001 / 1006
页数:6
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