Retinopathy of prematurity after sildenafil treatment

被引:3
作者
Fuwa, Kazumasa [1 ]
Hosono, Shigeharu [1 ]
Nagano, Nobuhiko [1 ]
Takahashi, Shori [1 ]
Nakashima, Motohiro [2 ]
机构
[1] Nihon Univ, Sch Med, Dept Pediat & Child Hlth, Itabashi Ku, Oyaguchi 30-1, Tokyo 1738610, Japan
[2] Nihon Univ, Sch Med, Dept Visual Sci, Div Ophthalmol,Itabashi Ku, Tokyo, Japan
关键词
oxygen; phosphodiesterase; 6; preterm infant; retinopathy of prematurity; sildenafil; ADULT-POPULATION; LYMPHOMA; CHILDREN;
D O I
10.1111/ped.13187
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Sildenafil (SIL) is used as a rescue treatment for severe bronchopulmonary dysplasia and pulmonary arterial hypertension. SIL inhibits phosphodiesterase 6 (PDE6) as well as PDE5. Therefore, it is controversial as to whether SIL increases the risk of retinopathy of prematurity (ROP).
引用
收藏
页码:360 / 361
页数:2
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