共 4 条
Retinopathy of prematurity after sildenafil treatment
被引:3
作者:
Fuwa, Kazumasa
[1
]
Hosono, Shigeharu
[1
]
Nagano, Nobuhiko
[1
]
Takahashi, Shori
[1
]
Nakashima, Motohiro
[2
]
机构:
[1] Nihon Univ, Sch Med, Dept Pediat & Child Hlth, Itabashi Ku, Oyaguchi 30-1, Tokyo 1738610, Japan
[2] Nihon Univ, Sch Med, Dept Visual Sci, Div Ophthalmol,Itabashi Ku, Tokyo, Japan
关键词:
oxygen;
phosphodiesterase;
6;
preterm infant;
retinopathy of prematurity;
sildenafil;
ADULT-POPULATION;
LYMPHOMA;
CHILDREN;
D O I:
10.1111/ped.13187
中图分类号:
R72 [儿科学];
学科分类号:
100202 ;
摘要:
Sildenafil (SIL) is used as a rescue treatment for severe bronchopulmonary dysplasia and pulmonary arterial hypertension. SIL inhibits phosphodiesterase 6 (PDE6) as well as PDE5. Therefore, it is controversial as to whether SIL increases the risk of retinopathy of prematurity (ROP).
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页码:360 / 361
页数:2
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