Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A

被引:37
作者
Lau, Susanna K. P. [2 ,3 ]
Li, Kenneth S. M.
Chau, Kam-yu
So, Lok-yee [4 ]
Lee, Rodney A. [5 ]
Lau, Yu-lung [6 ]
Chan, Kwok-hung
Lim, Wilina W. L. [7 ]
Woo, Patrick C. Y. [1 ,2 ,3 ]
Yuen, Kwok-yung [2 ,3 ]
机构
[1] Univ Hong Kong, Dept Microbiol, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, State Key Lab Emerging Infect Dis, Hong Kong, Hong Kong, Peoples R China
[3] Univ Hong Kong, Res Ctr Infect & Immunol, Hong Kong, Hong Kong, Peoples R China
[4] Pamela Youde Nethersole Eastern Hosp, Dept Paediat & Adolescent Med, Hong Kong, Hong Kong, Peoples R China
[5] Pamela Youde Nethersole Eastern Hosp, Dept Pathol, Hong Kong, Hong Kong, Peoples R China
[6] Univ Hong Kong, Dept Paediat & Adolescent Med, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China
[7] Ctr Hlth Protect, Publ Hlth Lab Ctr, Hong Kong, Hong Kong, Peoples R China
关键词
PEDIATRIC-PATIENTS; TYPE-4; INFECTIONS; CORONAVIRUS HKU1; RAPID DIAGNOSIS; OUTBREAK; CHILDREN; SEQUENCE; ADULT;
D O I
10.1128/JCM.00047-09
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.
引用
收藏
页码:1549 / 1552
页数:4
相关论文
共 20 条
  • [11] Clinical features and complete genome characterization of a distinct human rhinovirus (HRV) genetic previously undetected HRV cluster, probably representing a species, HRV-C, associated with acute respiratory illness in children
    Lau, Susanna K. P.
    Yip, Cyril C. Y.
    Tsoi, Hoi-wah
    Lee, Rodney A.
    So, Lok-yee
    Lau, Yu-lung
    Chan, Kwok-hung
    Woo, Patrick C. Y.
    Yuen, Kwok-yung
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2007, 45 (11) : 3655 - 3664
  • [12] Coronavirus HKU1 and other coronavirus infections in Hong Kong
    Lau, Susanna K. P.
    Woo, Patrick C. Y.
    Yip, Cyril C. Y.
    Tse, Herman
    Tsoi, Hol-wah
    Cheng, Vincent C. C.
    Lee, Paul
    Tang, Bone S. F.
    Cheung, Chris H. Y.
    Lee, Rodney A.
    So, Lok-yee
    Lau, Yu-lung
    Chan, Kwok-hung
    Yuen, Kwok-yung
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 2006, 44 (06) : 2063 - 2071
  • [13] Parainfluenza virus type 4 infections in pediatric patients
    Lindquist, SW
    Darnule, A
    Istas, A
    Demmler, GJ
    [J]. PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1997, 16 (01) : 34 - 38
  • [14] Human parainfluenza type 4 infection: a case report highlighting pathogenicity and difficulties in rapid diagnosis in the post-transplant setting
    Miall, F
    Rye, A
    Fraser, M
    Hunter, A
    Snowden, JA
    [J]. BONE MARROW TRANSPLANTATION, 2002, 29 (06) : 541 - 542
  • [15] Prolonged outbreak of human parainfluenza virus 3 infection in a stem cell transplant outpatient department: Insights from molecular epidemiologic analysis
    Nichols, WG
    Erdman, DD
    Han, A
    Zukerman, C
    Corey, L
    Boeckh, M
    [J]. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2004, 10 (01) : 58 - 64
  • [16] INFECTIONS DUE TO PARAINFLUENZA VIRUS TYPE-4 IN CHILDREN
    RUBIN, EE
    QUENNEC, P
    MCDONALD, JC
    [J]. CLINICAL INFECTIOUS DISEASES, 1993, 17 (06) : 998 - 1002
  • [17] Human parainfluenza type 4 infections, Canada
    Vachon, Marie-Louise
    Dionne, Natasha
    Leblanc, Eric
    Moisan, Danielle
    Bergeron, Michel G.
    Boivin, Guy
    [J]. EMERGING INFECTIOUS DISEASES, 2006, 12 (11) : 1755 - 1758
  • [18] Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia
    Woo, PCY
    Lau, SKP
    Chu, CM
    Chan, KH
    Tsoi, HW
    Huang, Y
    Wong, BHL
    Wong, HL
    Poon, RWS
    Cai, JJ
    Luk, WK
    Poon, LLM
    Wong, SSY
    Guan, Y
    Peiris, JSM
    Yuen, KY
    [J]. JOURNAL OF VIROLOGY, 2005, 79 (02) : 884 - 895
  • [19] Cost-effectiveness of rapid diagnosis of viral respiratory tract infections in pediatric patients
    Woo, PCY
    Chiu, SS
    Seto, WH
    Peiris, M
    [J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1997, 35 (06) : 1579 - 1581
  • [20] Adult croup: A rare but more severe condition
    Woo, PCY
    Young, K
    Tsang, KWT
    Ooi, CGC
    Peiris, M
    Yuen, KY
    [J]. RESPIRATION, 2000, 67 (06) : 684 - 688