Clinical and Molecular Epidemiology of Human Parainfluenza Virus 4 Infections in Hong Kong: Subtype 4B as Common as Subtype 4A

被引:37
作者
Lau, Susanna K. P. [2 ,3 ]
Li, Kenneth S. M.
Chau, Kam-yu
So, Lok-yee [4 ]
Lee, Rodney A. [5 ]
Lau, Yu-lung [6 ]
Chan, Kwok-hung
Lim, Wilina W. L. [7 ]
Woo, Patrick C. Y. [1 ,2 ,3 ]
Yuen, Kwok-yung [2 ,3 ]
机构
[1] Univ Hong Kong, Dept Microbiol, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China
[2] Univ Hong Kong, State Key Lab Emerging Infect Dis, Hong Kong, Hong Kong, Peoples R China
[3] Univ Hong Kong, Res Ctr Infect & Immunol, Hong Kong, Hong Kong, Peoples R China
[4] Pamela Youde Nethersole Eastern Hosp, Dept Paediat & Adolescent Med, Hong Kong, Hong Kong, Peoples R China
[5] Pamela Youde Nethersole Eastern Hosp, Dept Pathol, Hong Kong, Hong Kong, Peoples R China
[6] Univ Hong Kong, Dept Paediat & Adolescent Med, Queen Mary Hosp, Hong Kong, Hong Kong, Peoples R China
[7] Ctr Hlth Protect, Publ Hlth Lab Ctr, Hong Kong, Hong Kong, Peoples R China
关键词
PEDIATRIC-PATIENTS; TYPE-4; INFECTIONS; CORONAVIRUS HKU1; RAPID DIAGNOSIS; OUTBREAK; CHILDREN; SEQUENCE; ADULT;
D O I
10.1128/JCM.00047-09
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
In this 1-year study, 35 (1.2%) of 2,912 nasopharyngeal aspirates were positive for human parainfluenza virus 4 (HPIV4) by reverse transcription-PCR. Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B.
引用
收藏
页码:1549 / 1552
页数:4
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