Preparation of pH-responsive AgNPs/polymer nanohybrids with controllable metal-enhanced fluorescence behavior

被引:11
作者
Ma, Hongjing [1 ]
Li, Aihua [2 ,3 ]
Xu, Yuanhong [1 ]
Zhang, Wenling [1 ]
Liu, Jingquan [1 ]
机构
[1] Qingdao Univ, Growing Base State Key Lab, Lab Fiber Mat & Modern Text, Coll Chem Sci & Engn, Qingdao 266071, Peoples R China
[2] Shandong Univ, Minist Educ, Key Lab Special Funct Aggregated Mat, Jinan 250100, Peoples R China
[3] Shandong Univ, Sch Chem & Chem Engn, Jinan 250100, Peoples R China
基金
中国国家自然科学基金;
关键词
Metal-enhanced fluorescence (MEF); RAFT polymerization; Silver nanoparticle; pH responsive polymer; GOLD NANOPARTICLES; SURFACE; DESIGN; NANOCRYSTALS; NANOSHELLS; SUBSTRATE; SULFIDE; SINGLE; PROBES;
D O I
10.1016/j.eurpolymj.2015.09.021
中图分类号
O63 [高分子化学(高聚物)];
学科分类号
070305 ; 080501 ; 081704 ;
摘要
Fabrication of metal-enhanced fluorescence (MEF) system with stimuli responsive "soft" shells is an efficient means to achieve tunable MEF behavior. In this article, pH responsive fluorophores modified polyacrylic acid (PM) with tunable chain length was synthesized via reversible addition fragmentation chain transfer (RAFT) polymerization using a rhodamine B (RB) functionalized RAFT agent, followed by the immobilization onto silver nanoparticles (AgNPs) via Ag-S coordination interaction to afford core-shell nanohybrids with AgNPs core, PM shell and RB fluorophores on the surface. TEM and XPS analysis revealed that the polymer was successfully linked onto AgNPs surface. Our results revealed that the fluorescent intensity of AgNPs/polymer core-shell nanohybrids was sensitive extremely to the environmental pH values. All the maximal fluorescence intensities were observed at around pH 2, but slightly different. The maximal fluorescent intensity at pH 2 increased with the increasing polymer chain length first and then decreased. When the degree of polymerization (DP) of polymer was designed at 150, the maximal MEF was obtained. The size change of the core-shell nanohybrids with different environmental value was also supported by DIS analysis, which also manifested that the tunable MEF behavior was sensitive to the distance between the AgNPs and fluorophores. These pH responsive AgNPs/polymer core-shell nanohybrids may envision potential applications in drug delivery, sensors and nanodevices. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:212 / 221
页数:10
相关论文
共 40 条
[1]   Metal-enhanced fluorescence: an emerging tool in biotechnology [J].
Aslan, K ;
Gryczynski, I ;
Malicka, J ;
Matveeva, E ;
Lakowicz, JR ;
Geddes, CD .
CURRENT OPINION IN BIOTECHNOLOGY, 2005, 16 (01) :55-62
[2]   Metal-enhanced fluorescence-based RNA sensing [J].
Aslan, K ;
Huang, J ;
Wilson, GM ;
Geddes, CD .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (13) :4206-4207
[3]   Size variation and optical absorption of sol-gel Ag nanoparticles doped SiO2 thin film [J].
Babapour, A. ;
Akhavan, O. ;
Moshfegh, A. Z. ;
Hosseini, A. A. .
THIN SOLID FILMS, 2006, 515 (02) :771-774
[4]   Fluorescence Enhancement by Au Nanostructures: Nanoshells and Nanorods [J].
Bardhan, Rizia ;
Grady, Nathaniel K. ;
Cole, Joseph R. ;
Joshi, Amit ;
Halas, Naomi J. .
ACS NANO, 2009, 3 (03) :744-752
[5]   The design and utility of polymer-stabilized iron-oxide nanoparticles for nanomedicine applications [J].
Boyer, Cyrille ;
Whittaker, Michael R. ;
Bulmus, Volga ;
Liu, Jingquan ;
Davis, Thomas P. .
NPG ASIA MATERIALS, 2010, 2 (01) :23-30
[6]   Modulation of the Surface Charge on Polymer-Stabilized Gold Nanoparticles by the Application of an External Stimulus [J].
Boyer, Cyrille ;
Whittaker, Michael R. ;
Chuah, Kyloon ;
Liu, Jingquan ;
Davis, Thomas P. .
LANGMUIR, 2010, 26 (04) :2721-2730
[7]   Design and Synthesis of Dual Thermoresponsive and Antifouling Hybrid Polymer/Gold Nanoparticles [J].
Boyer, Cyrille ;
Whittaker, Michael R. ;
Luzon, Mario ;
Davis, Thomas P. .
MACROMOLECULES, 2009, 42 (18) :6917-6926
[8]   Semiconductor nanocrystals as fluorescent biological labels [J].
Bruchez, M ;
Moronne, M ;
Gin, P ;
Weiss, S ;
Alivisatos, AP .
SCIENCE, 1998, 281 (5385) :2013-2016
[9]   Quantum dot bioconjugates for ultrasensitive nonisotopic detection [J].
Chan, WCW ;
Nie, SM .
SCIENCE, 1998, 281 (5385) :2016-2018
[10]   RAFT-Polymers with Single and Multiple Trithiocarbonate Groups as Uniform Gold-Nanoparticle Coatings [J].
Ebeling, Bastian ;
Vana, Philipp .
MACROMOLECULES, 2013, 46 (12) :4862-4871