EzEditor: a versatile sequence alignment editor for both rRNA- and protein-coding genes

被引:143
作者
Jeon, Yoon-Seong [1 ,2 ]
Lee, Kihyun [3 ]
Park, Sang-Cheol [1 ]
Kim, Bong-Soo [2 ]
Cho, Yong-Joon [2 ]
Ha, Sung-Min [3 ]
Chun, Jongsik [1 ,2 ,3 ]
机构
[1] Seoul Natl Univ, Interdisciplinary Program Bioinformat, Seoul, South Korea
[2] Seoul Natl Univ, ChunLab Inc, Seoul, South Korea
[3] Seoul Natl Univ, Sch Biol Sci, Seoul, South Korea
关键词
MULTIPLE ALIGNMENT; DNA; ENVIRONMENT;
D O I
10.1099/ijs.0.059360-0
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
EzEditor is a Java-based molecular sequence editor allowing manipulation of both DNA and protein sequence alignments for phylogenetic analysis. It has multiple features optimized to connect initial computer-generated multiple alignment and subsequent phylogenetic analysis by providing manual editing with reference to biological information specific to the genes under consideration. It provides various functionalities for editing rRNA alignments using secondary structure information. In addition, it supports simultaneous editing of both DNA sequences and their translated protein sequences for protein-coding genes. EzEditor is, to our knowledge, the first sequence editing software designed for both rRNA- and protein-coding genes with the visualization of biologically relevant information and should be useful in molecular phylogenetic studies. EzEditor is based on Java, can be run on all major computer operating systems and is freely available from http://sw.ezbiocloud.net/ezeditor/.
引用
收藏
页码:689 / 691
页数:3
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