The molecular mysteries underlying P-glycoprotein-mediated multidrug resistance

被引：15
|
作者：
Szakács, G [1 ]
Chen, GK [1 ]
Gottesman, MM [1 ]
机构：
[1] NCI, Cell Biol Lab, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
来源：
CANCER BIOLOGY & THERAPY | 2004年 / 3卷 / 04期
关键词：
multidrug resistance; P-glycoprotein; MDR1; ZNRD1; transcriptional regulation;
D O I：
10.4161/cbt.3.4.743
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：382 / 384
页数：3
相关论文
共 50 条
  • [41] P-glycoprotein-mediated multidrug resistance and lymphokine-activated killer cell susceptibility in ovarian carcinoma
    Savas, B
    Cole, SPC
    Tsuruo, T
    Pross, HF
    JOURNAL OF CLINICAL IMMUNOLOGY, 1996, 16 (06) : 348 - 357
  • [42] Modulation of P-glycoprotein-mediated multidrug resistance by acceleration of passive drug permeation across the plasma membrane
    Regev, Ronit
    Katzir, Hagar
    Yeheskely-Hayon, Daniella
    Eytan, Gera D.
    FEBS JOURNAL, 2007, 274 (23) : 6204 - 6214
  • [43] RS-33295-198 - A NOVEL, POTENT MODULATOR OF P-GLYCOPROTEIN-MEDIATED MULTIDRUG-RESISTANCE
    SLATE, DL
    BRUNO, NA
    CASEY, SM
    ZUTSHI, N
    GARVIN, LJ
    WU, H
    PFISTER, JR
    ANTICANCER RESEARCH, 1995, 15 (03) : 811 - 814
  • [44] Carboxymethylcellulose-Based and Docetaxel-Loaded Nanoparticles Circumvent P-Glycoprotein-Mediated Multidrug Resistance
    Roy, Aniruddha
    Murakami, Mami
    Ernsting, Mark J.
    Hoang, Bryan
    Undzys, Elijus
    Li, Shyh-Dar
    MOLECULAR PHARMACEUTICS, 2014, 11 (08) : 2592 - 2599
  • [45] Lycorine Carbamate Derivatives for Reversing P-glycoprotein-Mediated Multidrug Resistance in Human Colon Adenocarcinoma Cells
    Sancha, Shirley A. R.
    Szemeredi, Nikoletta
    Spengler, Gabriella
    Ferreira, Maria-Jose U.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (03)
  • [46] Compounds from Chinese herbal medicines as reversal agents for P-glycoprotein-mediated multidrug resistance in tumours
    C. Li
    B.-Q. Sun
    X.-D. Gai
    Clinical and Translational Oncology, 2014, 16 : 593 - 598
  • [47] Inhibition of P-glycoprotein-mediated multidrug efflux by aminomethylene and ketomethylene analogs of reversins
    Koubeissi, Ali
    Raad, Imad
    Ettouati, Laurent
    Guilet, David
    Dumontet, Charles
    Paris, Joelle
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2006, 16 (21) : 5700 - 5703
  • [48] Reversal of P-glycoprotein-mediated multidrug resistance is induced by saikosaponin D in breast cancer MCF-7/adriamycin cells
    Li, Chun
    Guan, Xingang
    Xue, Haogang
    Wang, Peng
    Wang, Manli
    Gai, Xiaodong
    PATHOLOGY RESEARCH AND PRACTICE, 2017, 213 (07) : 848 - 853
  • [49] Reversal of P-glycoprotein-mediated Multidrug Resistance in SGC7901/VCR Cells by PPARγ Activation by Troglitazone
    Chen, Qing
    Zhou, Jie
    Jiang, Chunfang
    Chen, Juan
    JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES, 2010, 30 (03) : 326 - 331
  • [50] Reversal of P-glycoprotein-mediated multidrug resistance by 5,6,7,3′,4′-pentamethoxyflavone (sinensetin)
    Choi, CH
    Sun, KH
    An, CS
    Yoo, JC
    Hahm, KS
    Lee, IH
    Sohng, JK
    Kim, YC
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2002, 295 (04) : 832 - 840
12345