Experimental Therapies for Ebola Virus Disease: What Have We Learned?

被引：22

作者：

Hayden, Frederick G. ^{[1
]}

Friede, Martin ^{[2
]}

Bausch, Daniel G. ^{[2
]}

机构：

[1] Univ Virginia, Sch Med, Charlottesville, VA 22908 USA

[2] World Hlth Org, Geneva, Switzerland

来源：

JOURNAL OF INFECTIOUS DISEASES | 2017年 / 215卷 / 02期

基金：

英国惠康基金;

关键词：

Ebola; antivirals; immunotherapeutics; clinical research; HEMORRHAGIC-FEVER; NONHUMAN-PRIMATES; PERSISTENCE; PATIENT; FLUID;

D O I：

10.1093/infdis/jiw496

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

引用

页码：167 / 170

页数：4

共 31 条

[1]

[Anonymous], 2016, R D BLUEPR ACT PREV

[2] West Africa 2013: Re-examining Ebola [J].

Bausch, Daniel G. ;

Rojek, Amanda .

MICROBIOLOGY SPECTRUM, 2016, 4 (03)

[3]

Calain P., 2016, J MED ETHICS, P1, DOI DOI 10.1136/MEDETHICS-2016/103474

[4] Evaluating Clinical Trial Designs for Investigational Treatments of Ebola Virus Disease [J].

Cooper, Ben S. ;

Boni, Maciej F. ;

Pan-ngum, Wirichada ;

Day, Nicholas P. J. ;

Horby, Peter W. ;

Olliaro, Piero ;

Lang, Trudie ;

White, Nicholas J. ;

White, Lisa J. ;

Whitehead, John .

PLOS MEDICINE, 2015, 12 (04)

[5] A Randomized, Controlled Trial of ZMapp for Ebola Virus Infection [J].

Davey, Richard T., Jr. ;

Dodd, Lori ;

Proschan, Michael A. ;

Neaton, James ;

Nordwall, Jacquie Neuhaus ;

Koopmeiners, Joseph S. ;

Beigel, John ;

Tierney, John ;

Lane, H. Clifford ;

Fauci, Anthony S. ;

Massaquoi, Moses B. F. ;

Sahr, Foday ;

Malvy, Denis .

NEW ENGLAND JOURNAL OF MEDICINE, 2016, 375 (15) :1448-1456

[6] Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days [J].

Diallo, Boubacar ;

Sissoko, Daouda ;

Loman, Nicholas J. ;

Bah, Hadja Aissatou ;

Bah, Hawa ;

Worrell, Mary Claire ;

Conde, Lya Saidou ;

Sacko, Ramata ;

Mesfin, Samuel ;

Loua, Angelo ;

Kalonda, Jacques Katomba ;

Erondu, Ngozi A. ;

Dahl, Benjamin A. ;

Handrick, Susann ;

Goodfellow, Ian ;

Meredith, Luke W. ;

Cotten, Matthew ;

Jah, Umaru ;

Wadoum, Raoul Emeric Guetiya ;

Rollin, Pierre ;

Magassouba, N'Faly ;

Malvy, Denis ;

Anglaret, Xavier ;

Carroll, Miles W. ;

Aylward, Raymond Bruce ;

Djingarey, Mamoudou Harouna ;

Diarra, Abdoulaye ;

Formenty, Pierre ;

Keita, Sakoba ;

Guenther, Stephan ;

Rambaut, Andrew ;

Duraffour, Sophie .

CLINICAL INFECTIOUS DISEASES, 2016, 63 (10) :1353-1356

[7] Design of a Randomized Controlled Trial for Ebola Virus Disease Medical Countermeasures: PREVAIL II, the Ebola MCM Study [J].

Dodd, Lori E. ;

Proschan, Michael A. ;

Neuhaus, Jacqueline ;

Koopmeiners, Joseph S. ;

Neaton, James ;

Beigel, John D. ;

Barrett, Kevin ;

Lane, Henry Clifford ;

Davey, Richard T., Jr. .

JOURNAL OF INFECTIOUS DISEASES, 2016, 213 (12) :1906-1913

[8] First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease [J].

Dornemann, Jenny ;

Burzio, Chiara ;

Ronsse, Axelle ;

Sprecher, Armand ;

De Clerck, Hilde ;

Van Herp, Michel ;

Kolie, Marie-Claire ;

Yosifiva, Vesselina ;

Caluwaerts, Severine ;

McElroy, Anita K. ;

Antierens, Annick .

JOURNAL OF INFECTIOUS DISEASES, 2017, 215 (02) :171-174

[9] Experimental Treatment of Ebola Virus Disease with Brincidofovir [J].

Dunning, Jake ;

Kennedy, Stephen B. ;

Antierens, Annick ;

Whitehead, John ;

Ciglenecki, Iza ;

Carson, Gail ;

Kanapathipillai, Rupa ;

Castle, Lyndsey ;

Howell-Jones, Rebecca ;

Pardinaz-Solis, Raul ;

Grove, Jennifer ;

Scott, Janet ;

Lang, Trudie ;

Olliaro, Piero ;

Horby, Peter W. .

PLOS ONE, 2016, 11 (09)

[10] Experimental Treatment of Ebola Virus Disease with TKM-130803: A Single-Arm Phase 2 Clinical Trial [J].

Dunning, Jake ;

Sahr, Foday ;

Rojek, Amanda ;

Gannon, Fiona ;

Carson, Gail ;

Idriss, Baimba ;

Massaquoi, Thomas ;

Gandi, Regina ;

Joseph, Sebatu ;

Osman, Hassan K. ;

Brooks, Timothy J. G. ;

Simpson, Andrew J. H. ;

Goodfellow, Ian ;

Thorne, Lucy ;

Arias, Armando ;

Merson, Laura ;

Castle, Lyndsey ;

Howell-Jones, Rebecca ;

Pardinaz-Solis, Raul ;

Hope-Gill, Benjamin ;

Ferri, Mauricio ;

Grove, Jennifer ;

Kowalski, Mark ;

Stepniewska, Kasia ;

Lang, Trudie ;

Whitehead, John ;

Olliaro, Piero ;

Samai, Mohammed ;

Horby, Peter W. .

PLOS MEDICINE, 2016, 13 (04)

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