Colloidal RBC-Shaped, Hydrophilic, and Hollow Mesoporous Carbon Nanocapsules for Highly Efficient Biomedical Engineering

被引:204
作者
Chen, Yu [1 ]
Xu, Pengfei [2 ]
Wu, Meiying [1 ]
Meng, Qingshuo [2 ]
Chen, Hangrong [1 ]
Shu, Zhu [1 ]
Wang, Jin [1 ]
Zhang, Lingxia [1 ]
Li, Yaping [2 ]
Shi, Jianlin [1 ]
机构
[1] Chinese Acad Sci, State Lab High Performance Ceram & Superfine Micr, Shanghai Inst Ceram, Shanghai 200050, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai 201203, Peoples R China
基金
上海市自然科学基金;
关键词
BREAST-CANCER METASTASIS; SILICA NANOPARTICLES; DRUG-DELIVERY; CELLS; RELEASE; NANOSTRUCTURES; NANOMEDICINE; NANOSPHERES; DOXORUBICIN; INHIBITION;
D O I
10.1002/adma.201400303
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A facile and versatile synthetic route (templated framework pyrolysis) toward the construction of a new colloidal carbon nanosystem based on red blood cell (RBC)-shaped, hydrophilic, and hollow mesoporous carbon nanocapsules (HMCNs) is developed for highly efficient biomedical engineering, including stimuli-responsive drug release, inhibiting the metastasis, and circumventing the multidrug resistance of cancer cells.
引用
收藏
页码:4294 / 4301
页数:8
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