Systemic administration of STING agonist antibody-drug conjugates elicit potent anti-tumor immune responses with minimal induction of circulating cytokines

被引:21
作者
Bukhalid, Raghida A. [1 ]
Duvall, Jeremy R. [1 ]
Cetinbas, Naniye Malli [1 ]
Catcott, Kalli C. [1 ]
Avocetien, Kenneth [1 ]
Bentley, Keith W. [1 ]
Bradley, Stephen [1 ]
Carter, Tyler [1 ]
Chin, Chen-Ni [1 ]
Clardy, Susan [1 ]
Collins, Scott D. [1 ]
Eitas, Timothy [1 ]
Jones, Brian D. [1 ]
Kelleher, Eugene W. [1 ]
Mosher, Rebecca [1 ]
Nazzaro, Mark [1 ]
Protopopova, Marina [1 ]
Shaw, Pamela [1 ]
Slocum, Kelly [1 ]
Ter-Ovanesyan, Elena [1 ]
Qin, LiuLiang [1 ]
Thomas, Joshua D. [1 ]
Xu, Ling [1 ]
Yang, Liping [1 ]
Zurita, Jeffrey [1 ]
Toader, Dorin [1 ]
Damelin, Marc [1 ]
Lowinger, Timothy B. [1 ]
机构
[1] Mersana Therapeut Inc, Cambridge, MA USA
关键词
D O I
10.1158/1538-7445.AM2020-6706
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
6706
引用
收藏
页数:2
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