Functional "Janus" Annulus in Confined Channels

被引：51

作者：

Gao, Pengcheng ^{[1
]}

Hu, Lintong ^{[2
]}

Liu, Nannan ^{[1
]}

Yang, Zekun ^{[1
]}

Lou, Xiaoding ^{[1
]}

Zhai, Tianyou ^{[2
]}

Li, Huiqiao ^{[2
]}

Xia, Fan ^{[1
,3
]}

机构：

[1] Huazhong Univ Sci & Technol, Sch Chem & Chem Engn, Minist Educ, Key Lab Large Format Battery Mat & Syst, Wuhan 430074, Peoples R China

[2] Huazhong Univ Sci & Technol, Sch Mat Sci & Engn, State Key Lab Mat Proc & Die & Mould Technol, Wuhan 430074, Peoples R China

[3] Huazhong Univ Sci & Technol, Coll Life Sci & Technol, Inst Mat Med, Natl Engn Res Ctr Nanomed, Wuhan 430074, Peoples R China

来源：

ADVANCED MATERIALS | 2016年 / 28卷 / 03期

基金：

中国国家自然科学基金; 中国博士后科学基金;

关键词：

SINGLE-NUCLEOTIDE POLYMORPHISMS; NUCLEAR-PORE COMPLEX; NANOCHANNEL ARRAY; DNA; NANOPORES; TRANSPORT; LABEL; SENSORS; HYBRIDIZATION; MODULATION;

D O I：

10.1002/adma.201502344

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Scattered Au 3D nanoparticles form distinct functional regions with an uncovered internal surface in confined channels, named the "Janus" annulus. Electrochemical impedance spectroscopy responses to the variations in DNA self-assembly and hybridization in the channels decorated by the "Janus" annulus are presented. Single nucleotide mutations are further detected in a linear DNA chain, including terminal base polymorphisms.

引用

页码：460 / +

页数：7

共 47 条

[1] The molecular architecture of the nuclear pore complex [J].