Key Issues in Addressing the Comorbidity of Attention Deficit Hyperactivity Disorder and Pediatric Epilepsy
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作者:
Salpekar, Jay A.
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George Washington Univ, Sch Med, Childrens Natl Med Ctr, Ctr Neurosci & Behav Med, Washington, DC USAGeorge Washington Univ, Sch Med, Childrens Natl Med Ctr, Ctr Neurosci & Behav Med, Washington, DC USA
Salpekar, Jay A.
[1
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Mishra, Gaurav
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George Washington Univ, Sch Med, Childrens Natl Med Ctr, Ctr Neurosci & Behav Med, Washington, DC USAGeorge Washington Univ, Sch Med, Childrens Natl Med Ctr, Ctr Neurosci & Behav Med, Washington, DC USA
Mishra, Gaurav
[1
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机构:
[1] George Washington Univ, Sch Med, Childrens Natl Med Ctr, Ctr Neurosci & Behav Med, Washington, DC USA
Attention deficit hyperactivity disorder (ADHD) is a common comorbidity of epilepsy encountered by clinicians. However, relatively little information is available to guide optimal diagnostic and treatment strategies. Differentiating ADHD from effects of epilepsy requires careful history taking and emphasis upon characteristic symptoms and course of illness. Rating scales for ADHD are well validated and may aid clinical management. Use of antiepileptic drugs may cause cognitive or behavioral side effects yet may improve behavior in some cases. Historically, clinicians have been hesitant to treat ADHD comorbidity for fear of lowering the seizure threshold. However, an aggregate of recent evidence now suggests that stimulants may be well tolerated and effective for ADHD comorbid with epilepsy. Studies that further clarify pathophysiology and treatment outcomes are needed in order to enhance clinical efficacy and quality of life for this population. (C) 2014 Elsevier Inc. All rights reserved.
机构:
Pontificia Univ Catolica Rio Grande do Sul, Hosp Sao Lucas, Div Neurol, Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, Hosp Sao Lucas, Div Neurol, Porto Alegre, RS, Brazil
Neto, Felipe Kalil
Nunes, Magda L.
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Pontificia Univ Catolica Rio Grande do Sul, Hosp Sao Lucas, Div Neurol, Porto Alegre, RS, Brazil
Pontificia Univ Catolica Rio Grande do Sul, Sch Med, Porto Alegre, RS, Brazil
Pontificia Univ Catolica Rio Grande do Sul, Brain Inst InsCer, Porto Alegre, RS, BrazilPontificia Univ Catolica Rio Grande do Sul, Hosp Sao Lucas, Div Neurol, Porto Alegre, RS, Brazil
机构:
Natl Ctr Young People Epilepsy, Res Dept, Surrey RH7 6PW, England
Natl Ctr Young People Epilepsy, Dept Psychol, Surrey RH7 6PW, EnglandNatl Ctr Young People Epilepsy, Res Dept, Surrey RH7 6PW, England
机构:
Univ Joinville Reg UNIVILLE, Fac Med, Joinville, SC, Brazil
Univ Sao Paulo, Fac Med, Dept Neurol, Sao Paulo, BrazilUniv Joinville Reg UNIVILLE, Fac Med, Joinville, SC, Brazil
Koneski, Julio A. S.
Casella, Erasmo B.
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机构:
Univ Sao Paulo, Fac Med, Dept Neurol, Sao Paulo, Brazil
Univ Sao Paulo, Fac Med, Child Inst, Clin Hosp, Sao Paulo, BrazilUniv Joinville Reg UNIVILLE, Fac Med, Joinville, SC, Brazil