Xylomexicanins A and B, New Δ14,15-Mexicanolides from Seeds of the Chinese Mangrove Xylocarpus granatum

被引：0

作者：

Shen, Li-Ru ^{[1
]}

Dong, Mei ^{[2
]}

Guo, Dong ^{[3
]}

Yin, Bao-Wei ^{[1
]}

Zhang, Man-Li ^{[1
]}

Sha, Qing-Wen ^{[1
]}

Huo, Chang-Hong ^{[1
]}

Kiyota, Hiromasa ^{[4
]}

Suzuki, Nobuo ^{[5
]}

Cong, Bin ^{[2
]}

机构：

[1] Hebei Med Univ, Dept Med Nat Prod Chem, Sch Pharmaceut Sci, Shijiazhuang 050017, Hebei Prov, Peoples R China

[2] Hebei Med Univ, Coll Basic Med, Shijiazhuang 050017, Peoples R China

[3] New Drug R&D Co Ltd, N China Pharmaceut Grp Corp, Shijiazhuang 050035, Hebei Prov, Peoples R China

[4] Tohoku Univ, Dept Biosci & Biotechnol Future Bioind, Grad Sch Agr Sci, Aoba Ku, Sendai, Miyagi 9818555, Japan

[5] Chiba Univ, Dept Environm Biochem, Grad Sch Med, Chuo Ku, Chiba 2608670, Japan

来源：

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES | 2009年 / 64卷 / 1-2期

基金：

中国博士后科学基金; 日本学术振兴会;

关键词：

Xylocarpus granatum; Limonoids; Antiproliferative Activity; XYLOGRANATINS A-D; LIMONOIDS; MEXICANOLIDES; FRUIT; RSA;

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two new mexicanolide-type limonoids, named xylomexicanin A (1) and xylomexicanin B (2), were isolated from seeds of the Chinese mangrove Xylocarpus granatum. Their structures were elucidated on the basis of spectroscopic methods. Compound 1 exhibited antiproliferative activity against human breast carcinoma cells (KT), while 2 did not show inhibitory effects on eleven human tumour cell lines tested.

引用

页码：37 / 42

页数：6

共 47 条

[1] Two new mexicanolides from the fruit of the Chinese mangrove Xylocarpus granatum
Wu, J
Zhang, S
Song, Y
Xiao, ZH
Xiao, Q
Lia, QX
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2005, 60 (12): : 1291 - 1294
[2] Xylocarpins A and B, two new mexicanolides from the seeds of a Chinese mangrove Xylocarpus granatum:: NMR investigation in mixture
Li, Minyi
Wu, Jun
Zhang, Si
Xiao, Qiang
Li, Qingxin
MAGNETIC RESONANCE IN CHEMISTRY, 2007, 45 (08) : 705 - 709
[3] Xylogranatins A-D, new mexicanolides from the fruit of a Chinese mangrove Xylocarpus granatum
Wu, Jun
Zhang, Si
Li, Minyi
Zhou, Yuan
Xiao, Qiang
CHEMICAL & PHARMACEUTICAL BULLETIN, 2006, 54 (11) : 1582 - 1585
[4] Mexicanolides from the Seeds of a Krishna Mangrove, Xylocarpus moluccensis
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Yang, Xiao-Bo
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CHEMICAL & PHARMACEUTICAL BULLETIN, 2010, 58 (04) : 552 - 555
[5] New Limonoids from the Seeds of a Krishna Mangrove, Xylocarpus granatum
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CHEMISTRY & BIODIVERSITY, 2013, 10 (04) : 612 - 620
[6] The absolute stereochemistry of protoxylogranatin A -: a new protolimonoid from the seeds of Chinese mangrove Xylocarpus granatum
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Wu, Jun
Zhang, Si
Xiao, Qiang
Li, Qing-Xin
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2008, 10 (06) : 503 - 508
[7] Xyloccensins X1 and X2, two new mexicanolides from the fruit of a Chinese mangrove Xylocarpus granatum
Cheng, Fan
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ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2006, 61 (05): : 626 - 628
[8] Limonoids from the seeds of the marine mangrove Xylocarpus granatum
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Fan, Cheng-Qi
Lin, Li-Ping
Ding, Jian
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JOURNAL OF NATURAL PRODUCTS, 2007, 70 (04): : 682 - 685
[9] Limonoids from the Seeds of a Hainan Mangrove, Xylocarpus granatum
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JOURNAL OF NATURAL PRODUCTS, 2010, 73 (10): : 1672 - 1679
[10] Xylomexicanins E-H, new limonoids from Xylocarpus granatum
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TETRAHEDRON, 2014, 70 (30) : 4557 - 4562

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