What do grid cells contribute to place cell firing?

被引：103

作者：

Bush, Daniel ^{[1
,2
]}

Barry, Caswell ^{[3
]}

Burgess, Neil ^{[1
,2
]}

机构：

[1] UCL, Inst Cognit Neurosci, London WC1N 3AR, England

[2] UCL Inst Neurol, London WC1N 3BG, England

[3] UCL Dept Cell & Dev Biol, London WC1E 6BT, England

来源：

TRENDS IN NEUROSCIENCES | 2014年 / 37卷 / 03期

基金：

英国惠康基金; 英国医学研究理事会;

关键词：

place cells; grid cells; boundary vector cells; border cells; hippocampus; HIPPOCAMPAL ENSEMBLE CODE; HEAD-DIRECTION CELLS; LONG-TERM STABILITY; UNIT-ACTIVITY; SPATIAL REPRESENTATION; PATH-INTEGRATION; NEURAL REPRESENTATIONS; VENTRAL HIPPOCAMPUS; PHASE PRECESSION; RAT HIPPOCAMPUS;

D O I：

10.1016/j.tins.2013.12.003

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The unitary firing fields of hippocampal place cells are commonly assumed to be generated by input from entorhinal grid cell modules with differing spatial scales. Here, we review recent research that brings this assumption into doubt. Instead, we propose that place cell spatial firing patterns are determined by environmental sensory inputs, including those representing the distance and direction to environmental boundaries, while grid cells provide a complementary self-motion related input that contributes to maintaining place cell firing. In this view, grid and place cell firing patterns are not successive stages of a processing hierarchy, but complementary and interacting representations that work in combination to support the reliable coding of large-scale space.

引用

页码：136 / 145

页数：10

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