Motoring around the Golgi

被引:167
作者
Allan, VJ [1 ]
Thompson, HM
McNiven, MA
机构
[1] Univ Manchester, Sch Biol Sci, Manchester M13 9PT, Lancs, England
[2] Mayo Clin & Mayo Fdn, Dept Biochem & Mol Biol, Rochester, MN 55905 USA
关键词
D O I
10.1038/ncb1002-e236
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The Golgi apparatus is a dynamic organelle through which nascent secretory and transmembrane proteins are transported, post-translationally modified and finally packaged into carrier vesicles for transport along the cytoskeleton to a variety of destinations. In the past decade, studies have shown that a number of 'molecular motors' are involved in maintaining the proper structure and function of the Golgi apparatus. Here, we review just some of the many functions performed by these mechanochemical enzymes-dyneins, kinesins, myosins and dynamin-in relation to the Golgi apparatus.
引用
收藏
页码:E236 / E242
页数:7
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