GC-MS Analysis of the Composition of the Extracts and Essential Oil from Myristica fragrans Seeds Using Magnesium Aluminometasilicate as Excipient

被引：36
作者：
Matulyte, Inga [1 ]
Marksa, Mindaugas [2 ]
Ivanauskas, Liudas [2 ]
Kalveniene, Zenona [1 ,3 ]
Lazauskas, Robertas [4 ]
Bernatoniene, Jurga [1 ,3 ]
机构：
[1] Lithuanian Univ Hlth Sci, Med Acad, Dept Drug Technol & Social Pharm, LT-50161 Kaunas, Lithuania
[2] Lithuanian Univ Hlth Sci, Med Acad, Dept Analyt & Toxicol Chem, LT-50161 Kaunas, Lithuania
[3] Lithuanian Univ Hlth Sci, Med Acad, Inst Pharmaceut Technol, LT-50161 Kaunas, Lithuania
[4] Lithuanian Univ Hlth Sci, Med Acad, Inst Physiol & Pharmacol, LT-50161 Kaunas, Lithuania
来源：
MOLECULES | 2019年 / 24卷 / 06期
关键词：
Myristica fragrans; nutmeg; essential oil; extract; magnesium aluminometasilicate; hydrodistillation; ANTIOXIDANT; L; SPICES; INHIBITION; COMPONENTS;
D O I：
10.3390/molecules24061062
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Myristica fragrans (f. Myristicaceae) seeds are better known as a spice, but their chemical compounds may have a pharmacological effect. The yield of their composition of extracts and essential oils differs due to different methodologies. The aim of this study was to evaluate an excipient materialmagnesium aluminometasilicateand to determine its influence on the qualitative composition of nutmeg extracts and essential oils. Furthermore, we wanted to compare the yield of essential oil. The extracts were prepared by maceration (M) and ultrasound bath-assisted extraction (UAE), and the essential oilby hydrodistillation (HD). Conventional methods (UAE, HD) were modified with magnesium aluminometasilicate. The samples were analyzed by gas chromatography-mass spectrometry (GC-MS) method. From 16 to 19 chemical compounds were obtained using UAE with magnesium aluminometasilicate, while only 8 to 13 compounds were obtained using UAE without an excipient. Using our conditions and plant material, for the first time eight new chemical compounds in nutmeg essential oil were identified. Two of these compounds (-amorphene and cis--bergamotene) were obtained with the use of excipient, the other six (-copaene, bergamotene, citronellyl decanoate, cubebol, cubenene, orthodene) by conventional hydrodistillation. Magnesium aluminometasilicate significantly increased the quantity of sabinene (from 6.53% to 61.42%) and limonene (from 0% to 5.62%) in essential oil. The yield of the essential oil from nutmeg seeds was significantly higher using magnesium aluminometasilicate; it increased from 5.25 +/- 0.04% to 10.43 +/- 0.09%.
引用
收藏
页数：12
相关论文
共 44 条
  • [1] ADAMS R P., 2004, Identification of essential oil components by gas chromatography/ quadrupole mass spectroscopy
  • [2] Activity guided characterization of antioxidant components from essential oil of Nutmeg (Myristica fragrans)
    Adiani, Vanshika
    Gupta, Sumit
    Chatterjee, Suchandra
    Variyar, Prasad S.
    Sharma, Arun
    [J]. JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE, 2015, 52 (01): : 221 - 230
  • [3] [Anonymous], 2017, INT J 2 METAB, DOI [10.21448/ijsm.375120, DOI 10.21448/IJSM.375120]
  • [4] [Anonymous], AFR J BIOTECHNOL
  • [5] [Anonymous], 2016, ASIAN J PHARM CLIN R
  • [6] [Anonymous], 2015, J ESSENT OIL BEAR PL
  • [7] Ashish D.G., 2013, Journal of Genetic Engineering and Biotechnology, V11, P25, DOI DOI 10.1016/J.JGEB.2012.12.001
  • [8] Azwanida N.N., 2015, MED AROMAT PLANTS, V4, P412, DOI [DOI 10.4172/2167-0412.1000196, 10.4172/2167-0412.1000196, 10.4172/2167-0412.1000196,0412, DOI 10.4172/2167-0412.1000196,0412]
  • [9] Barceloux DG, 2009, DM-DIS MON, V55, P318, DOI [10.1016/j.disamonth.2009.03.008, 10.1016/j.disamonth.2009.03.002, 10.1016/j.disamonth.2009.03.007, 10.1016/j.disamonth.2009.03.006, 10.1016/j.disamonth.2009.03.003, 10.1016/j.disamonth.2009.03.005, 10.1016/j.disamonth.2009.03.010, 10.1016/j.disamonth.2009.03.011, 10.1016/j.disamonth.2009.03.004]
  • [10] Pressurized liquid extraction of active ingredients (ginsenosides) from medicinal plants using non-ionic surfactant solutions
    Choi, MPK
    Chan, KKC
    Leung, HW
    Huie, CW
    [J]. JOURNAL OF CHROMATOGRAPHY A, 2003, 983 (1-2) : 153 - 162
12345