Modulation of cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADH and cytochrome b5

被引：1
|
作者：
Indra, Radek [1 ]
Moserova, Michaela [1 ]
Volker, Arlt M. [2 ]
Stiborova, Marie [1 ]
机构：
[1] Charles Univ Prague, Dept Biochem, Fac Sci, Prague 2, Czech Republic
[2] Kings Coll London, Analyt & Environm Sci Div, MRC PHE Ctr Environm & Hlth, London WC2R 2LS, England
来源：
TOXICOLOGY LETTERS | 2014年 / 229卷
关键词：
D O I：
10.1016/j.toxlet.2014.06.525
中图分类号：
R99 [毒物学（毒理学）];
学科分类号：
100405 ;
摘要：
P-3.16
引用
收藏
页码：S150 / S150
页数：1
相关论文
共 50 条
  • [1] Modulation of human cytochrome P450 1A1-mediated oxidation of benzo[a]pyrene by NADPH:cytochrome P450 oxidoreductase and cytochrome b5
    Indra, Radek
    Moserova, Michaela
    Kroftova, Natalie
    Sulc, Miroslav
    Martinkova, Marketa
    Adam, Vojtech
    Eckschlager, Tomas
    Kizek, Rene
    Arlt, Volker M.
    Stiborova, Marie
    NEUROENDOCRINOLOGY LETTERS, 2014, 35 : 105 - 113
  • [2] NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene
    Stiborova, Marie
    Indra, Radek
    Moserova, Michaela
    Frei, Eva
    Schmeiser, Heinz H.
    Kopka, Klaus
    Philips, David H.
    Arlt, Volker M.
    CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 29 (08) : 1325 - 1334
  • [3] NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene (vol 29, pg 1325, 2016)
    Stiborova, Marie
    Indra, Radek
    Moserova, Michaela
    Frei, Eva
    Schmeiser, Heinz H.
    Kopka, Klaus
    Phillips, David H.
    Arlt, Volker M.
    CHEMICAL RESEARCH IN TOXICOLOGY, 2016, 29 (09) : 1571 - 1571
  • [4] NADH: cytochrome b5 reductase and cytochrome b5 act as sole electron donors to human cytochrome P450 1A1-catalyzed oxidation and DNA adduct formation by benzo[a]pyrene
    Stiborova, M.
    Radek, I.
    Moserova, M.
    Frei, E.
    Kopka, K.
    Phillips, D. H.
    Arlt, V. M.
    TOXICOLOGY LETTERS, 2016, 258 : S96 - S96
  • [5] Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study
    Indra, Radek
    Moserova, Michaela
    Sulc, Miroslav
    Frei, Eva
    Stiborova, Marie
    NEUROENDOCRINOLOGY LETTERS, 2013, 34 : 55 - 63
  • [6] Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5/P450 reductase null (HBRN) mice
    Reed, Lindsay
    Mrizova, Iveta
    Barta, Frantisek
    Indra, Radek
    Moserova, Michaela
    Kopka, Klaus
    Schmeiser, Heinz H.
    Wolf, C. Roland
    Henderson, Colin J.
    Stiborova, Marie
    Phillips, David H.
    Arlt, Volker M.
    ARCHIVES OF TOXICOLOGY, 2018, 92 (04) : 1625 - 1638
  • [7] Cytochrome b5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b5/P450 reductase null (HBRN) mice
    Lindsay Reed
    Iveta Mrizova
    Frantisek Barta
    Radek Indra
    Michaela Moserova
    Klaus Kopka
    Heinz H. Schmeiser
    C. Roland Wolf
    Colin J. Henderson
    Marie Stiborova
    David H. Phillips
    Volker M. Arlt
    Archives of Toxicology, 2018, 92 : 1625 - 1638
  • [8] The effect of cytochrome b5 on a reaction cycle of cytochrome P450 1A1
    Indra, R.
    Milichovsky, J.
    Moserova, M.
    Arlt, V. M.
    Stiborova, M.
    TOXICOLOGY LETTERS, 2015, 238 (02) : S286 - S286
  • [9] A role of cytochrome b5 in CYP1A1-mediated oxidation of benzo[a]pyrene and other substrates
    Stiborova, M.
    Indra, R.
    Hodek, P.
    Frei, E.
    Martinek, V.
    Schmeiser, H.
    Arlt, V.
    FEBS OPEN BIO, 2018, 8 : 20 - 21
  • [10] The roles of cytochrome b5 in cytochrome P450 reactions
    Porter, TD
    JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2002, 16 (06) : 311 - 316
12345