Non-coding RNAs in gastric cancer

被引：49

作者：

Xie, Shanshan ^{[1
,2
,3
]}

Chang, Yongxia ^{[2
,3
,4
]}

Jin, Hao ^{[2
,3
,4
]}

Yang, Feng ^{[2
,3
,4
]}

Xu, Yanjun ^{[5
]}

Yan, Xiaoyi ^{[4
]}

Lin, Aifu ^{[6
]}

Shu, Qiang ^{[1
]}

Zhou, Tianhua ^{[2
,3
,4
,7
]}

机构：

[1] Zhejiang Univ, Childrens Hosp, Sch Med, Hangzhou 310052, Peoples R China

[2] Zhejiang Univ, Dept Cell Biol, Sch Med, Affiliated Hosp 2, Hangzhou 310058, Peoples R China

[3] Zhejiang Univ, Canc Inst, Sch Med, Affiliated Hosp 2, Hangzhou 310058, Peoples R China

[4] Zhejiang Univ, Canc Ctr, Hangzhou 310058, Peoples R China

[5] Chinese Acad Sci, Zhejiang Canc Hosp, Univ Chinese Acad Sci, Inst Canc Res & Basic Med Sci,Canc Hosp, Hangzhou 310022, Peoples R China

[6] Zhejiang Univ, Coll Life Sci, MOE Lab Biosyst Homeostasis & Protect, Hangzhou 310058, Peoples R China

[7] Univ Toronto, Dept Mol Genet, Toronto, ON M5S 1A8, Canada

来源：

CANCER LETTERS | 2020年 / 493卷

基金：

中国国家自然科学基金;

关键词：

lncRNA; miRNA; circRNA; piRNA; Stomach cancer; REGULATES CELL-PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; POOR-PROGNOSIS; PROMOTES PROLIFERATION; CIRCULATING MICRORNAS; CYCLE PROGRESSION; DOWN-REGULATION; TUMOR INVASION; IN-VITRO; MIGRATION;

D O I：

10.1016/j.canlet.2020.06.022

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Non-coding RNAs (ncRNAs) are functional RNA molecules that play crucial regulatory roles in many fundamental biological processes. The dysregulation of ncRNAs is significantly associated with the progression of human cancers, including gastric cancer. In this review, we have summarized the oncogenic or tumorsuppressive roles and the regulatory mechanisms of lncRNAs, miRNAs, circRNAs and piRNAs, and have discussed their potential as biomarkers or therapeutic targets in gastric cancer.

引用

页码：55 / 70

页数：16

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