An Efficient Green Synthesis of a New Class of α-Aminophosphonates under Microwave Irradiation Conditions in the Presence of PS/PTSA

被引：5
作者：
Gangireddy, Chandra Sekhar Reddy [1 ,2 ,3 ]
Chinthaparthi, Radha Rani [2 ,3 ]
Mudumala, Veeranarayana Reddy [2 ]
Mamilla, Madhav [3 ]
Arigala, Uma Ravi Sankar [2 ]
机构：
[1] Sri Venkateswara Coll Engn, Dept Chem, Tirupati 517507, Andhra Pradesh, India
[2] Sri Venkateswara Univ, Dept Chem, Tirupati 517502, Andhra Pradesh, India
[3] Sri Venkateswara Degree & PG Coll, Dept Chem, Kadapa 16003, India
来源：
HETEROATOM CHEMISTRY | 2014年 / 25卷 / 03期
关键词：
ONE-POT SYNTHESIS; CATALYZED 3-COMPONENT SYNTHESIS; KABACHNIK-FIELDS REACTION; SOLVENT-FREE; AMINO-PHOSPHONATES; ASSISTED SYNTHESIS; DERIVATIVES; ACIDS;
D O I：
10.1002/hc.21147
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A highly efficient, catalyst-free, and regioselective synthesis of structurally diverse spirooxindole-fused phosphorous heterocycle derivatives was constructed in good yields by means of a three-component domino reaction of isatins, dichlorophenylphosphine or phenyl phosphorodichloridite, and o-aminophenol in tetrahydrofuran reflux. The advantages of this method include high efficiency, mild reaction conditions, and environmentally benign reagents. These spirooxindole-fused phosphorous heterocycles are promising candidates for drug discovery.
引用
收藏
页码：147 / 156
页数：10
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