Comparative evaluation of pulpal repair after direct pulp capping using stem cell therapy and biodentine: An animal study

被引：11

作者：

Amin, Laila E. ^{[1
,2
]}

Montaser, Marmar ^{[1
]}

机构：

[1] Mansoura Univ, Fac Dent, Mansoura, Egypt

[2] Horus Univ, Fac Dent, Dumyat, Egypt

来源：

AUSTRALIAN ENDODONTIC JOURNAL | 2021年 / 47卷 / 01期

关键词：

biodentine; dycal; pulp capping; pulp regeneration; stem cells; MINERAL TRIOXIDE AGGREGATE; DENTAL-PULP; CALCIUM HYDROXIDE; DIFFERENTIATION; CEMENT; TEETH;

D O I：

10.1111/aej.12463

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

The response of the dentin-pulp complex in rat teeth was investigated after direct capping with biodentine with or without bone marrow-derived stem cells (BMDSCs). Following mechanical exposure, pulps were randomly capped with one of the followings materials: calcium hydroxide, biodentine or 1 x 10(5) BMDSCs mL(-1) + biodentine. Histological examination was performed by light microscopy after 1, 3 and 5 weeks. Inflammatory reaction, necrotic tissue formation and calcific bridge formation were scored. Analysis showed that compared with the effects of calcium hydroxide or biodentine, BMDSCs + biodentine substantially reduced inflammatory reaction and necrotic tissue while promoting calcified tissue formation. Therefore, the combination of biodentine and BMDSCs could potentially stimulate pulp tissue regeneration after direct pulp capping.

引用

页码：11 / 19

页数：9

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