Prediction and validation of DXA-derived appendicular lean soft tissue mass by ultrasound in older adults

被引:41
作者
Abe, Takashi [1 ,3 ]
Thiebaud, Robert S. [2 ]
Loenneke, Jeremy P. [3 ]
Young, Kaelin C. [4 ]
机构
[1] Natl Inst Fitness & Sports Kanoya, Dept Sports & Life Sci, Kanoya, Kagoshima 8912393, Japan
[2] Texas Wesleyan Univ, Dept Kinesiol, Ft Worth, TX USA
[3] Univ Mississippi, Sch Appl Sci, Dept Hlth Exercise Sci & Recreat Management, Oxford, MS USA
[4] Edward Via Coll Osteopath Med, Dept Cell Biol & Physiol, Auburn, AL USA
关键词
Aging; Skeletal muscle mass; B-mode ultrasonography; DXA; SKELETAL-MUSCLE MASS; FAT-FREE MASS; JAPANESE ADULTS; THICKNESS MEASUREMENTS; BODY-COMPOSITION; MEN; WOMEN; ASSOCIATION; SARCOPENIA; EQUATIONS;
D O I
10.1007/s11357-015-9853-2
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
The purpose of this study was to develop regression-based prediction equations for estimating dual-energy X-ray absorptiometry (DXA)-derived appendicular lean soft tissue mass (aLM) using ultrasound and to investigate the validity of these equations in 102 Caucasian adults aged 50 to 76 years. The subjects were randomly separated into two groups: 71 in the model-development group (41 men and 30 women) and 31 in the cross-validation group (18 men and 13 women). aLM was measured using a DXA, and muscle thickness (MT) was measured using ultrasound at 9 sites. Step-wise linear regression analysis was used to determine predictive models for DXA-derived aLM from MT variables, sex, and age. A number of ultrasound prediction equations for estimation of aLM were developed and then cross-validated in a subsample of older adults. The results indicated that ultrasound MT and MT x height can be used to accurately and reliably estimate DXA-derived aLM in older Caucasian adults.
引用
收藏
页码:1 / 10
页数:10
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