Occipital atrophy is associated with visual hallucinations in Alzheimer's disease

被引：68

作者：

Holroyd, S ^{[1
]}

Shepherd, ML ^{[1
]}

Downs, JH ^{[1
]}

机构：

[1] Univ Virginia, Hlth Sci Ctr, Sch Med,Dept Neurosurg, Dept Psychiat Med,Neurovisualizat Lab,Virginia Ne, Charlottesville, VA 22908 USA

来源：

JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES | 2000年 / 12卷 / 01期

关键词：

D O I：

10.1176/jnp.12.1.25

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In this study of patients with Alzheimer's disease (AD), patients with visual hallucinations were compared with patients who did not have visual hallucinations to determine if selective occipital lobe atrophy is associated with visual hallucinations. Seven AD patients with visual hallucinations were matched by cognitive score to 7 AD patients without visual hallucinations and 3-D MRI images obtained. A ratio of measured occipital volumes to whole brain volumes was compared between the two groups. AD patients with visual hallucinations had a significantly smaller occipital/whole brain ratio than AD patients without visual hallucinations. These results suggest visual hallucinations in AD may be associated with neuropathology of the occipital lobe.

引用

页码：25 / 28

页数：4

共 17 条

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