Vaccine Therapies for Breast Cancer

被引：31
作者：
Burke, Erin E. [1 ]
Kodumudi, Krithika [2 ]
Ramamoorthi, Ganesan [2 ]
Czerniecki, Brian J. [3 ]
机构：
[1] H Lee Moffitt Canc Ctr & Res Inst, 12902 Magnolia Dr, Tampa, FL 33612 USA
[2] H Lee Moffitt Canc Ctr & Res Inst, Clin Sci Lab Dept, 12902 Magnolia Dr, Tampa, FL 33612 USA
[3] H Lee Moffitt Canc Ctr & Res Inst, Dept Breast Oncol, 12902 Magnolia Dr, Tampa, FL 33612 USA
来源：
SURGICAL ONCOLOGY CLINICS OF NORTH AMERICA | 2019年 / 28卷 / 03期
关键词：
Breast cancer; Vaccine therapy; Oncodrivers; Breast cancer immunity; GROUP-STUDY I-01; HER2/NEU E75 VACCINE; CLINICAL-TRIAL; SIGNALING PATHWAYS; INTERFERON-GAMMA; DENDRITIC CELLS; KLH VACCINE; DNA VACCINE; RECURRENCE; EXPRESSION;
D O I：
10.1016/j.soc.2019.02.004
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Vaccines can be a cost effective preventive measure for both primary prevention of disease and prevention of disease recurrence. Several vaccines targeting breast cancer oncodrivers are currently being tested in clinical trials. Whereas clinical response rates to breast cancer vaccines have been modest despite the induction of strong antitumor T cell responses, it is through these approaches that valuable insight and knowledge have been gained about tumor immunology. With the emergence of new immunotherapies, there is renewed excitement for effective breast cancer vaccine development.
引用
收藏
页码：353 / +
页数：16
相关论文
共 60 条
  • [1] Tumor-cell number and viability as quality and efficacy parameters of autologous virus-modified cancer vaccines in patients with breast or ovarian cancer
    Ahlert, T
    Sauerbrei, W
    Bastert, G
    Ruhland, S
    Bartik, B
    Simiantonaki, N
    Schumacher, J
    Hacker, B
    Schumacher, M
    Schirrmacher, V
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 1997, 15 (04) : 1354 - 1366
  • [2] Peptide vaccines of the HER-2/neu dimerization loop are effective in inhibiting mammary tumor growth in vivo
    Allen, Stephanie D.
    Garrett, Joan T.
    Rawale, Sharad V.
    Jones, Audra L.
    Phillips, Gary
    Forni, Guido
    Morris, John C.
    Oshima, Robert G.
    Kaumaya, Pravin T. P.
    [J]. JOURNAL OF IMMUNOLOGY, 2007, 179 (01) : 472 - 482
  • [3] [Anonymous], ASCO M
  • [4] Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835]
    Apostolopoulos, Vasso
    Pietersz, Geoffrey A.
    Tsibanis, Anastasios
    Tsikkinis, Annivas
    Drakaki, Heleni
    Loveland, Bruce E.
    Piddlesden, Sara J.
    Plebanski, Magdalena
    Pouniotis, Dodie S.
    Alexis, Michael N.
    McKenzie, Ian F.
    Vassilaros, Stamatis
    [J]. BREAST CANCER RESEARCH, 2006, 8 (03)
  • [5] Treatment of HER2-positive breast cancer: current status and future perspectives
    Arteaga, Carlos L.
    Sliwkowski, Mark X.
    Osborne, C. Kent
    Perez, Edith A.
    Puglisi, Fabio
    Gianni, Luca
    [J]. NATURE REVIEWS CLINICAL ONCOLOGY, 2012, 9 (01) : 16 - 32
  • [6] The Impact of HER2/neu Expression Level on Response to the E75 Vaccine: From US Military Cancer Institute Clinical Trials Group Study I-01 and I-02
    Benavides, Linda C.
    Gates, Jeremy D.
    Carmichael, Mark G.
    Patel, Ritesh
    Holmes, Jarrod P.
    Hueman, Matthew T.
    Mittendorf, Elizabeth A.
    Craig, Dianna
    Stojadinovic, Alexander
    Ponniah, Sathibalan
    Peoples, George E.
    [J]. CLINICAL CANCER RESEARCH, 2009, 15 (08) : 2895 - 2904
  • [7] First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer patients
    Berinstein, Neil L.
    Karkada, Mohan
    Morse, Michael A.
    Nemunaitis, John J.
    Chatta, Gurkamal
    Kaufman, Howard
    Odunsi, Kunle
    Nigam, Rita
    Sammatur, Leeladhar
    MacDonald, Lisa D.
    Weir, Genevieve M.
    Stanford, Marianne M.
    Mansour, Marc
    [J]. JOURNAL OF TRANSLATIONAL MEDICINE, 2012, 10
  • [8] Autoantibodies to aberrantly glycosylated MUC1 in early stage breast cancer are associated with a better prognosis
    Blixt, Ola
    Bueti, Deanna
    Burford, Brian
    Allen, Diane
    Julien, Sylvain
    Hollingsworth, Michael
    Gammerman, Alex
    Fentiman, Ian
    Taylor-Papadimitriou, Joyce
    Burchell, Joy M.
    [J]. BREAST CANCER RESEARCH, 2011, 13 (02):
  • [9] Cancer. org, 2018, CANC FACTS FIG 2015
  • [10] Cintolo JA, 2012, FUTURE ONCOL, V8, P1273, DOI [10.2217/FON.12.125, 10.2217/fon.12.125]
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