Functions of inorganic polyphosphates in eukaryotic cells: a coat of many colours

被引：28

作者：

Azevedo, Cristina ^{[1
]}

Saiardi, Adolfo

机构：

[1] UCL, MRC Lab Mol Cell Biol, Cell Biol Unit, London WC1E 6BT, England

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 2014年 / 42卷

基金：

英国医学研究理事会;

关键词：

DAPI staining; inorganic polyphosphate; ion channel; metabolism; sol-gel transition; transcription regulation; INOSITOL PYROPHOSPHATES; SACCHAROMYCES-CEREVISIAE; ESCHERICHIA-COLI; IDENTIFICATION; PURIFICATION; METABOLISM; MOLECULE;

D O I：

10.1042/BST20130111

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

PolyP (inorganic polyphosphate) is a linear polymer of tens to hundreds of orthophosphate residues linked by high-energy phosphoanhydride bonds. This polymer is present in all living organisms from bacteria to mammals. Until recently, most of the studies on polyP have focused on its function in prokaryotes. In prokaryotes, polyP has been implicated in many unrelated processes ranging from basic metabolism to structural functions. However, polyp analysis and function in higher eukaryotes has been gaining momentum recently. In the present review, we mainly aim to discuss the proposed intracellular functions of polyP in higher eukaryotes and its detection methods.

引用

页码：98 / 102

页数：5

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