Management of proliferative lupus nephritis

被引：0

作者：

Monroy Trujillo, Jose M. ^{[1
]}

Fine, Derek M. ^{[1
]}

机构：

[1] Johns Hopkins Univ Hosp, Div Nephrol, 1830 E Monument St,Suite 416, Baltimore, MD 21287 USA

来源：

PANMINERVA MEDICA | 2016年 / 58卷 / 04期

关键词：

Lupus nephritis; Biopsy; Lupus erythematosus; systemic; MYCOPHENOLATE-MOFETIL; KIDNEY BIOPSY; INDUCTION TREATMENT; THERAPY; CYCLOPHOSPHAMIDE; BIOLOGICS; EFFICACY; TRIALS;

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Kidney abnormalities are present in up to 60% of patients with systemic lupus. Proliferative lupus nephritis is one of the most serious manifestation and requires rapid recognition and treatment. Kidney biopsy plays an essential role in the management and prognosis of proliferative lupus nephritis. Treatment includes and induction phase with systemic steroids and antiproliferative therapy. This is followed by a maintenance phase to prevent the risk of relapses. Cytotmdc therapy carries significant side effects and complications. Further research is needed to establish the role of biologics in the management of proliferative lupus nephritis.

引用

页码：286 / 293

页数：8

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