Long-term effect of a nurse-led psychosocial intervention on health-related quality of life in patients with head and neck cancer: a randomised controlled trial

被引:62
作者
van der Meulen, I. C. [1 ,2 ,3 ]
May, A. M. [1 ]
de Leeuw, J. R. J. [1 ]
Koole, R. [2 ,3 ]
Oosterom, M. [1 ]
Hordijk, G-J [2 ,3 ]
Ros, W. J. G. [1 ]
机构
[1] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, NL-3508 GA Utrecht, Netherlands
[2] Univ Med Ctr Utrecht, Dept Oral & Maxillofacial Surg, NL-3508 GA Utrecht, Netherlands
[3] Univ Med Ctr Utrecht, Dept Otorhinolaryngol, NL-3508 GA Utrecht, Netherlands
关键词
head and neck cancer; health-related quality of life; depressive symptoms; psychosocial; intervention; nurse; DEPRESSIVE SYMPTOMS; SURVIVORS; ANXIETY; NEED;
D O I
10.1038/bjc.2013.733
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Background: Head and neck cancer (HNC) patients are prone to have a poor health-related quality of life after cancer treatment. This study investigated the effect of the nurse counselling and after intervention (NUCAI) on the health-related quality of life and depressive symptoms of HNC patients between 12 and 24 months after cancer treatment. Methods: Two hundred and five HNC patients were randomly allocated to NUCAI (N = 103) or usual care (N = 102). The 12-month nurse-led NUCAI is problem-focused and patient-driven and aims to help HNC patients manage with the physical, psychological and social consequences of their disease and its treatment. Health-related quality of life was evaluated with the EORTC QLQ-C30 and QLQ H&N35. Depressive symptoms were evaluated with the CES-D. Results: At 12 months the intervention group showed a significant (P<0.05) improvement in emotional and physical functioning, pain, swallowing, social contact, mouth opening and depressive symptoms. At 18 months, global quality of life, role and emotional functioning, pain, swallowing, mouth opening and depressive symptoms were significantly better in the intervention group than in the control group, and at 24 months emotional functioning and fatigue were significantly better in the intervention group. Conclusion: The NUCAI effectively improved several domains of health-related quality of life and depressive symptoms in HNC patients and would seem a promising intervention for implementation in daily clinical practice.
引用
收藏
页码:593 / 601
页数:9
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