Studies on the synthesis of NG-nitro-L-arginine derivatives and their effects on septic shock

被引：1

作者：

Zhao, M ^{[1
]}

Wang, C

Gu, MD

Peng, SQ

Yang, JK

Zhou, KX

Wu, SZ

机构：

[1] Beijing Med Univ, Coll Pharmaceut Sci, Beijing 100083, Peoples R China

[2] Guang Zhou Tonghe Hosp, Guangzhou 510515, Peoples R China

来源：

PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY | 2000年 / 30卷 / 03期

关键词：

D O I：

10.1080/10826060008544961

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

(HCl . N-G - NO2 - Arg)(2) Lys - OCH3, (HCl . N-G - NO2 - Arg)(2)Lys-OH, [(HCl . N-G - NO2 - Arg)(2)Lys](2)Lys - OCH3, and [(HCl . N-G - NO2-Arg)(2)Lys](2) Lys-OH were synthesized by use of a solution method. Their effect on septic shock was studied in vivo. The results indicate that increasing the number of N-G-NO2-Arg residues in a molecule may be useful to improve the response to septic shock.

引用

页码：241 / 246

页数：6

共 8 条

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