NECROTIC SKIN LESION IN A DOG ATTRIBUTED TO Loxosceles (BROWN SPIDER) BITE: A CASE REPORT

被引:4
作者
Machado, L. H. A. [1 ]
Antunes, M. I. P. P.
Mazini, A. M.
Sakate, M.
Torres-Neto, R.
Fabris, V. E. [2 ]
Vailati, M. C. F.
Lourenco, M. L. G.
机构
[1] UNESP, Fac Med Vet & Zootecnia, Dept Clin, Vet Med & Anim Husb Sch, BR-18618000 Botucatu, SP, Brazil
[2] UNESP, Botucatu Med Sch, Dept Pathol, BR-18618000 Botucatu, SP, Brazil
关键词
Loxosceles; dermonecrotic toxin; dogs; VENOM; EFFICACY;
D O I
10.1590/S1678-91992009000300017
中图分类号
R99 [毒物学(毒理学)];
学科分类号
100405 ;
摘要
Envenomations caused by Loxosceles (brown spider) have been reported throughout the world. Clinical signs associated to bites of these spiders involve dermonecrotic lesions and intense local inflammatory response, besides systemic manifestations such as intravascular hemolysis, thrombocytopenia, disseminated intravascular coagulation and acute renal failure. The present study aimed to report and to describe dermonecrotic lesions probably caused by a Loxosceles envenomation in a four year-old poodle female dog, treated at the Dermatology Service of the Veterinary Hospital of the Veterinary Medicine and Animal Husbandry School, Sao Paulo State University, Botucatu, Brazil. Initially, the animal presented two skin lesions with blackish aspect that evolved into ulcerative crusts. The owner reported the presence of a brown spider near the place where the animal spent most of the time. Histological examination of lesions revealed necrosis of the epidermis extending to adnexa and panniculi, which is compatible with Loxosceles bite reaction. The animal was treated with systemic antibiotic and local curatives. Lesions healed by second intention in two months.
引用
收藏
页码:572 / 581
页数:10
相关论文
共 29 条
[1]  
Barbaro K.C., 2003, ANIMAIS PECONHENTOS, P160
[2]  
BICUDO PL, 2003, ANIMAIS PECONHENTOS, P437
[3]   Brown spiders and loxoscelism [J].
da Silva, PH ;
da Silveira, RB ;
Appel, MH ;
Mangili, OC ;
Gremski, W ;
Veiga, SS .
TOXICON, 2004, 44 (07) :693-709
[4]   Histological findings after brown recluse spider envenomation [J].
Elston, DM ;
Eggers, JS ;
Schmidt, WE ;
Storrow, AB ;
Doe, RH ;
McGlasson, D ;
Fischer, JR .
AMERICAN JOURNAL OF DERMATOPATHOLOGY, 2000, 22 (03) :242-246
[5]  
Frezza RM., 2007, REV BRAS PROM SAUDE, V20, P133
[6]   LOXOSCELISM [J].
FUTRELL, JM .
AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1992, 304 (04) :261-267
[7]  
GFELLER RW, 2006, MANUAL TOXICOLOGIA E, P79
[8]  
Gross TL, 2005, SKIN DISEASES OF THE DOG AND CAT: CLINICAL AND HISTOPATHOLOGIC DIAGNOSIS, 2ND EDITION, P342
[9]  
Haddad V. Jr., 1999, Anais Brasileiros de Dermatologia, V74, P441
[10]   Loxoscelism: Old obstacles, new directions [J].
Hogan, CJ ;
Barbaro, KC ;
Winkel, K .
ANNALS OF EMERGENCY MEDICINE, 2004, 44 (06) :608-624