Microwave-assisted synthesis of phenylpyrimidine derivatives via Suzuki-Miyaura reactions in water

被引：18

作者：

Le, Yi ^{[1
,2
,3
]}

Zhang, Yan ^{[2
]}

Wang, Qin ^{[2
]}

Rao, Nian ^{[2
]}

Li, Dan ^{[2
]}

Liu, Li ^{[2
,3
]}

Ouyang, Guiping ^{[1
,2
,3
]}

Yan, Longjia ^{[2
,3
]}

机构：

[1] Guizhou Univ, Ctr Res & Dev Fine Chem,State Local Joint Lab Com, State Key Lab Breeding Base Green Pesticide & Agr, Key Lab Green Pesticide & Agr Bioengn,Minist Educ, Guiyang 550025, Peoples R China

[2] Guizhou Univ, Sch Pharmaceut Sci, Guiyang 550025, Peoples R China

[3] Guizhou Univ, Guizhou Engn Lab Synthet Drugs, Guiyang 550025, Peoples R China

来源：

TETRAHEDRON LETTERS | 2021年 / 68卷

关键词：

Phenylpyrimidine; Microwave; Suzuki-Miyaura; Water; Biguanidine;

D O I：

10.1016/j.tetlet.2021.152903

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient method was developed to prepare biphenylpyrimidine scaffolds via a Suzuki-Miyaura coupling reaction. In this procedure, the products were synthesized under microwave irradiation in water and analogues of biguanidine were employed as ligands. (C) 2021 Elsevier Ltd. All rights reserved.

引用

页数：4

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