Risk factors for enterococcal urinary tract infections: a multinational, retrospective cohort study

被引:8
作者
Turjeman, Adi [1 ,2 ]
Babich, Tanya [1 ,2 ]
Pujol, Miquel [3 ]
Carratala, Jordi [3 ]
Shaw, Evelyn [3 ]
Gomila-Grange, Aina [3 ,4 ]
Vuong, Cuong [5 ]
Addy, Ibironke [5 ]
Wiegand, Irith [5 ]
Grier, Sally [6 ]
MacGowan, Alasdair [6 ]
Vank, Christiane [5 ]
Cuperus, Nienke [7 ]
van den Heuvel, Leo [7 ]
Leibovici, Leonard [1 ,2 ]
Eliakim-Raz, Noa [1 ,2 ]
机构
[1] Beilinson Med Ctr, Rabin Med Ctr, Dept Med E, 39 Jabotinsky Rd, IL-49100 Petah Tiqwa, Israel
[2] Tel Aviv Univ, Sackler Fac Med, Tel Aviv, Israel
[3] Inst Salud Carlos III ISCIII, Spanish Network Res Infect Dis REIPI RD12 0015, Inst Invest Biomed Bellvitge IDIBELL, Dept Infect Dis,Hosp Univ Bellvitge, Madrid, Spain
[4] Hosp Univ Parc Tauli, Dept Infect Dis, Barcelona, Spain
[5] AiCuris Antiinfect Cures GmbH, Wuppertal, Germany
[6] Southmead Hosp, North Bristol NHS Trust, Dept Infect Sci, Bristol, Avon, England
[7] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
关键词
Complicated urinary tract infection (UTI); Enterococcus; Antibiotic stewardship; Risk factors;
D O I
10.1007/s10096-021-04207-4
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Complicated urinary tract infection (cUTI) is a frequent cause of morbidity. In this multinational retrospective cohort study, we aimed to demonstrate risk factors for enterococcal UTI. Univariate and multivariate analyses of risk factors for enterococcal infection were performed. Among 791 hospitalized patients with cUTI, enterococci accounted for approximately 10% of cases (78/791). Risk factors for enterococcal UTI in multivariable analysis were male gender, age range of 55-75 years, catheter-associated UTI, and urinary retention. This information may assist treating physicians in their decision-making on prescribing empiric anti-enterococcus treatment to hospitalized patients presenting with cUTI and thus improve clinical outcomes.
引用
收藏
页码:2005 / 2010
页数:6
相关论文
共 30 条
[1]  
Agudelo HiguitaN.I. Huycke., 2014, Enterococci: From Commensals to Leading Causes of Drug Resistant Infection
[2]  
[Anonymous], DATA ECDC SURVEILLAN
[3]   Incidence, Risk Factors, and Outcomes for Enterococcus spp. Blood Stream Infections: A Population-Based Study [J].
Billington, E. O. ;
Phang, S. H. ;
Gregson, D. B. ;
Pitout, J. D. D. ;
Ross, T. ;
Church, D. L. ;
Laupland, K. B. ;
Parkins, M. D. .
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES, 2014, 26 :76-82
[4]   A European perspective on nosocomial urinary tract infections I.: Report on the microbiology workload, etiology and antimicrobial susceptibility (ESGNI-003 study) [J].
Bouza, E ;
San Juan, R ;
Muñoz, P ;
Voss, A ;
Kluytmans, J .
CLINICAL MICROBIOLOGY AND INFECTION, 2001, 7 (10) :523-531
[5]   A European perspective on nosocomial urinary tract infections II.: Report on incidence, clinical characteristics and outcome (ESGNI-004 study) [J].
Bouza, E ;
San Juan, R ;
Muñoz, P ;
Voss, A ;
Kluytmans, J .
CLINICAL MICROBIOLOGY AND INFECTION, 2001, 7 (10) :532-542
[6]   Emerging resistance problems and future perspectives in pharmacotherapy for complicated urinary tract infections [J].
Chen, Yen-Hsu ;
Ko, Wen-Chien ;
Hsueh, Po-Ren .
EXPERT OPINION ON PHARMACOTHERAPY, 2013, 14 (05) :587-596
[7]   The microbiology of bacteriuria in men: a 5-year study at a Veterans' Affairs hospital [J].
Cornia, Paul B. ;
Takahashi, Traci A. ;
Lipsky, Benjamin A. .
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE, 2006, 56 (01) :25-30
[8]   Population-based epidemiologic analysis of acute pyelonephritis [J].
Czaja, Christopher A. ;
Scholes, Delia ;
Hooton, Thomas M. ;
Stamm, Walter E. .
CLINICAL INFECTIOUS DISEASES, 2007, 45 (03) :273-280
[9]   Risk Factors for Treatment Failure and Mortality Among Hospitalized Patients With Complicated Urinary Tract Infection: A Multicenter Retrospective Cohort Study (RESCUING Study Group) [J].
Eliakim-Raz, Noa ;
Babitch, Tanya ;
Shaw, Evelyn ;
Addy, Ibironke ;
Wiegand, Irith ;
Vank, Christiane ;
Torre-Vallejo, Laura ;
Joan-Miquel, Vigo ;
Steve, Morris ;
Grier, Sally ;
Stoddart, Margaret ;
Nienke, Cuperus ;
Leo, van den Heuvel ;
Cuong Vuong ;
MacGowan, Alasdair ;
Carratala, Jordi ;
Leibovici, Leonard ;
Pujol, Miquel ;
Tancheva, Dora ;
Vatcheva-Dobrevska, Rossitza ;
Tsiodras, Sotirios ;
Roilides, Emmanuel ;
Varkonyi, Istvan ;
Bodnar, Judit ;
Farkas, Aniko ;
Zak-Doron, Yael ;
Carmeli, Yehuda ;
Mangoni, Emanuele Durante ;
Mussini, Cristina ;
Petrosillo, Nicola ;
Vata, Andrei ;
Hristea, Adriana ;
Origuen, Julia ;
Rodriguez-Bano, Jesus ;
ArzuYetkin ;
Saltoglu, Nese .
CLINICAL INFECTIOUS DISEASES, 2019, 68 (01) :29-36
[10]   Candida Urinary Tract Infection: Pathogenesis [J].
Fisher, John F. ;
Kavanagh, Kevin ;
Sobel, Jack D. ;
Kauffman, Carol A. ;
Newman, Cheryl A. .
CLINICAL INFECTIOUS DISEASES, 2011, 52 :S437-S451