Auditory brainstem response in preterm infants with bilirubin encephalopathy

被引:5
作者
Okumura, Akihisa [1 ]
Kitai, Yukihiro [2 ]
Arai, Hiroshi [2 ]
Hayakawa, Masahiro [3 ]
Maruo, Yoshihiro [4 ]
Kusaka, Takashi [5 ]
Kunikata, Tetsuya [6 ]
Kumada, Satoko [7 ]
Morioka, Ichiro [8 ]
机构
[1] Aichi Med Univ, Dept Pediat, 1-1 Yazako Karimata, Nagakute, Aichi 4801195, Japan
[2] Bobath Mem Hosp, Dept Pediat Neurol, Joto Ku, 1-6-5 Higashinakahama, Osaka 5360023, Japan
[3] Nagoya Univ Hosp, Div Neonatol, Ctr Maternal Neonatal Care, Showa Ku, 65 Tsurumai Cho, Nagoya, Aichi 4668560, Japan
[4] Shiga Univ Med Sci, Dept Pediat, Seta Tsukinowa Cho, Otsu, Shiga 5202192, Japan
[5] Kagawa Univ, Dept Pediat, Fac Med, 1750-1 Ikenobe, Miki, Kagawa 7610793, Japan
[6] Saitama Med Univ Hosp, Div Neonatal Med, Dept Pediat, 38 Morohongo Moroyama Machi, Saitama 3500495, Japan
[7] Tokyo Metropolitan Neurol Hosp, Dept Neuropediatr, 2-6-1 Musashidai, Fuchu, Tokyo 1830042, Japan
[8] Nihon Univ, Dept Pediat & Child Hlth, Sch Med, Itabashi Ku, 30-1 Oyaguchi Kamimachi, Tokyo 1738610, Japan
关键词
Auditory neuropathy; Auditory brainstem response; Bilirubin encephalopathy; Preterm infants; Verbal communication;
D O I
10.1016/j.earlhumdev.2021.105319
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Aim: To clarify auditory brainstem response (ABR) in preterm infants with bilirubin encephalopathy and the relationships between ABR and clinical variables. Method: We retrospectively reviewed the ABR waveforms of 56 preterm infants with BE and graded them as "no response", "abnormal interwave separation", or "normal". Patient backgrounds, the peak total bilirubin level, the bilirubin/albumin ratio, verbal communication ability, and newborn hearing screening test results from an automated ABR evaluation had been collected during an earlier nationwide survey. Results: The frequency of abnormal ABR findings decreased with age. Verbal communication tended to be poorer in patients with more severe ABR abnormalities. ABR findings improved in 7 of 29 infants with available serial ABR data. Both gestational age and the peak total bilirubin level were relatively lower in patients with than in those without improved ABR findings. Newborn hearing screening using automated ABR evaluation yielded data consistent with manual ABR findings in 16 of 20 patients who underwent both examinations. Conclusions: ABR abnormalities in preterm infants with bilirubin encephalopathy may improve over time, especially in those with a lower gestational age and peak total bilirubin level. Newborn hearing screening using automated ABR may fail to detect abnormalities in some infants.
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页数:6
相关论文
共 27 条
[1]   Auditory Brainstem Response Improvements in Hyperbillirubinemic Infants [J].
Abdollahi, Farzaneh Zamiri ;
Ahmadi, Tayebeh ;
Manchaiah, Vinaya ;
Lotfi, Yones .
JOURNAL OF AUDIOLOGY AND OTOLOGY, 2016, 20 (01) :13-16
[2]   Bilirubin Binding Capacity in the Preterm Neonate [J].
Amin, SanjiV B. .
CLINICS IN PERINATOLOGY, 2016, 43 (02) :241-+
[3]   Bilirubin and serial auditory brainstem responses in premature infants [J].
Amin, SB ;
Ahlfors, C ;
Orlando, MS ;
Dalzell, LE ;
Merle, KS ;
Guillet, R .
PEDIATRICS, 2001, 107 (04) :664-670
[4]   The clinical syndrome of bilirubin-induced neurologic dysfunction [J].
Bhutani, Vinod K. ;
Johnson-Hamerman, Lois .
SEMINARS IN FETAL & NEONATAL MEDICINE, 2015, 20 (01) :6-13
[5]  
Cianfrone F, 2018, J Neonatal Perinatal Med, V11, P87, DOI 10.3233/NPM-181744
[6]   Hearing loss in children with very low birth weight: current review of epidemiology and pathophysiology [J].
Cristobal, R. ;
Oghalai, J. S. .
ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2008, 93 (06) :1462-1468
[7]   The spectrum of bilirubin neurotoxicity in term and near-term babies with hyperbilirubinemia: Does outcome improve with time? [J].
ElTatawy, Sarah S. ;
Elmazzahy, Esraa A. ;
El Shennawy, Amira M. ;
Madani, Hanan A. ;
Abou Youssef, Hazem ;
Iskander, Iman F. .
EARLY HUMAN DEVELOPMENT, 2020, 140
[8]   Serum Bilirubin and Bilirubin/Albumin Ratio as Predictors of Bilirubin Encephalopathy [J].
Iskander, Iman ;
Gamaleldin, Rasha ;
El Houchi, Salma ;
El Shenawy, Amira ;
Seoud, Iman ;
El Gharbawi, Nesrin ;
Abou-Youssef, Hazem ;
Aravkin, Aleksandr ;
Wennberg, Richard P. .
PEDIATRICS, 2014, 134 (05) :E1330-E1339
[9]   A multicenter evaluation of how many infants with permanent hearing loss pass a two-stage otoacoustic emissions/automated auditory brainstem response newborn hearing screening protocol [J].
Johnson, JL ;
White, KR ;
Widen, JE ;
Gravel, JS ;
James, M ;
Kennalley, T ;
Maxon, AB ;
Spivak, L ;
Sullivan-Mahoney, M ;
Vohr, BR ;
Weirather, Y ;
Holstrum, J .
PEDIATRICS, 2005, 116 (03) :663-672
[10]   Investigation of the freely available easy-to-use software 'EZR' for medical statistics [J].
Kanda, Y. .
BONE MARROW TRANSPLANTATION, 2013, 48 (03) :452-458