Nontoxic organic solvents identified using an a priori approach with Hansen solubility parameters

被引:17
作者
Nakamura, Daisuke [1 ]
Hirano, Minoru [1 ]
Ohta, Riichiro [1 ]
机构
[1] Toyota Cent Res & Dev Labs Inc, Nagakute, Aichi 4801192, Japan
关键词
CELLS;
D O I
10.1039/c7cc01434a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Nontoxicities of organic solvents were predicted using Hansen solubility parameters and various truly nontoxic solvents were identified according to the prediction. The nontoxicity of solvents originates from their exhibition of poor solubility or low diffusivity toward cell constituents and good stability against hydrolytic degradation.
引用
收藏
页码:4096 / 4099
页数:4
相关论文
共 16 条
  • [1] Abbott S., Hansen Solubility Parameters in Practice (HSPiP)
  • [2] CHEMICAL BURNS OF THE RABBIT CORNEA
    CARPENTER, CP
    SMYTH, HF
    [J]. AMERICAN JOURNAL OF OPHTHALMOLOGY, 1946, 29 (11) : 1363 - 1372
  • [3] SURVIVAL OF MAMMALS BREATHING ORGANIC LIQUIDS EQUILIBRATED WITH OXYGEN AT ATMOSPHERIC PRESSURE
    CLARK, LC
    GOLLAN, F
    [J]. SCIENCE, 1966, 152 (3730) : 1755 - &
  • [4] BEHAVIOR OF CELLS AT FLUID INTERFACES
    GIAEVER, I
    KEESE, CR
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (01): : 219 - 222
  • [5] GRANT W.M., 1974, TOXICOLOGY EYE
  • [6] Hansen C.M., 2007, Hansen's Solubility Parameters: A User's Handbook
  • [7] Polymer science applied to biological problems: Prediction of cytotoxic drug interactions with DNA
    Hansen, Charles M.
    [J]. EUROPEAN POLYMER JOURNAL, 2008, 44 (09) : 2741 - 2748
  • [8] A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
    Kang, Hyun-Wook
    Lee, Sang Jin
    Ko, In Kap
    Kengla, Carlos
    Yoo, James J.
    Atala, Anthony
    [J]. NATURE BIOTECHNOLOGY, 2016, 34 (03) : 312 - +
  • [9] Fluorous solvent for cell culture
    Kasuya, Maria Carmelita Z.
    Wen, Xiaonan
    Hatanaka, Kenichi
    Akashi, Kageyasu
    [J]. JOURNAL OF FLUORINE CHEMISTRY, 2011, 132 (11) : 978 - 981
  • [10] Kirwin C. J., 1981, PATTYS HYGIENE TOXIC