Effect of maternal anxiety on maternal serum and fetal cord blood cortisol

被引：12

作者：

Keshavarzi, Farahnaz ^{[1
]}

Farnia, Vahid ^{[2
]}

Yazdchi, Katayoun ^{[1
]}

Najafi, Farid ^{[3
]}

Brand, Serge ^{[4
]}

Bajoghli, Hafez ^{[5
]}

Nankali, Anisodoleh ^{[1
]}

Salmanzadeh, Habib ^{[6
]}

机构：

[1] Kermanshah Univ Med Sci, Dept Obstet & Gynecol, Kermanshah 0831, Iran

[2] Kermanshah Univ Med Sci, Behav Sci Res Ctr, Dept Psychiat, Kermanshah 0831, Iran

[3] Kermanshah Univ Med Sci, Dept Hlth Serv, Kermanshah 0831, Iran

[4] Univ Basel, Ctr Affect Stress & Sleep Disorders, Psychiat Clin, Basel, Switzerland

[5] Univ Tehran Med Sci, Tehran, Iran

[6] Kermanshah Univ Med Sci, Student Res Ctr, Kermanshah 0831, Iran

来源：

ASIA-PACIFIC PSYCHIATRY | 2014年 / 6卷 / 04期

关键词：

anxiety; cortisol; fetal blood; maternal; pregnancy; PRENATAL STRESS; HPA AXIS; CHILD; GLUCOCORTICOIDS; OUTCOMES;

D O I：

10.1111/appy.12125

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

IntroductionPrenatal exposure to maternal anxiety and inappropriate levels of glucocorticoids may influence intrauterine growth and affect later health outcomes. We examined the relationship between maternal anxiety, maternal serum, and fetal cord blood cortisol. MethodsEighty-four pregnant women with gestational age above 37 weeks admitted for elective caesarian section were studied. The Spielberger State-Trait Anxiety Inventory was used to assess maternal anxiety. Maternal blood was sampled immediately before caesarean section. Cord blood sample was taken immediately after birth. Multiple regression analysis was performed. ResultsMaternal trait anxiety score, maternal serum cortisol, and neonatal weight were associated with the fetal cord blood cortisol (r=0.21, P=0.04). Bivariate correlation analysis revealed a positive correlation between maternal trait anxiety and fetal cord blood cortisol (r=0.21, P=0.03). ConclusionsThese data suggested that high maternal trait anxiety increases fetus cord blood cortisol and may regulate fetal growth.

引用

页码：435 / 439

页数：5

共 19 条

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